Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health. - Lockhart SM; Muso M; Zvetkova I; Lam BYH; Ferrari A; Schoenmakers E; Duckett K; Leslie J; Collins A; Romartínez-Alonso B; Tadross JA; Jia R; et al. (Nature metabolism, 2024)