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Evidence-based guidelines for drug dosing in intravitreal injections in silicone oil-filled eyes: Pharmacokinetics, safety, and optimal dosage.

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Title: Evidence-based guidelines for drug dosing in intravitreal injections in silicone oil-filled eyes: Pharmacokinetics, safety, and optimal dosage.
Authors: Ferro Desideri L; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland., Sim PY; Moorfields Eye Hospital NHS Foundation Trust, London, UK., Bernardi E; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland., Paschon K; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland., Roth J; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland., Fung AT; Westmead and Central (Save Sight Institute) Clinical Schools, Specialty of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, Australia; Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia., Wu XN; Department of Ophthalmology, Fremantle Hospital, Perth, Australia., Chou HD; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan and College of Medicine, Chang Gung University, Taoyuan, Taiwan., Henderson R; Moorfields Eye Hospital NHS Foundation Trust, London, UK., Tsui E; UCLA Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Berrocal M; Berrocal & Associates, Department of Ophthalmology, University of Puerto Rico, San Juan, Puerto Rico, USA., Chhablani J; Medical Retina and Vitreoretinal Surgery, University of Pittsburgh School of Medicine, Pittsburg, PA, USA., Wykoff CC; Retina Consultants of Texas; Blanton Eye Institute Houston Methodist Hospital, Houston, TX, USA., Cheung CMG; Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Eye-ACP, Duke-NUS Medical School, Singapore., Querques G; Department of Ophthalmology, University Vita-Salute IRCCS San Raffaele Scientific Institute, Milan, Italy., Melo GB; Federal University of São Paulo, UNIFESP, São Paulo, SP, Brazil., Subhi Y; Department of Ophthalmology, Copenhagen University Hospital, Copenhagen, Denmark., Loewenstein A; Department of Ophthalmology, Tel Aviv Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Kiilgaard JF; Department of Ophthalmology, Copenhagen University Hospital, Copenhagen, Denmark., Zinkernagel M; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland., Anguita R; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Moorfields Eye Hospital NHS Foundation Trust, London, UK. Electronic address: rodrigoanguita@gmail.com.
Source: Survey of ophthalmology [Surv Ophthalmol] 2025 Jan-Feb; Vol. 70 (1), pp. 96-105. Date of Electronic Publication: 2024 Sep 27.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 0404551 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3304 (Electronic) Linking ISSN: 00396257 NLM ISO Abbreviation: Surv Ophthalmol Subsets: MEDLINE
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  Data: Evidence-based guidelines for drug dosing in intravitreal injections in silicone oil-filled eyes: Pharmacokinetics, safety, and optimal dosage.
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  Data: <searchLink fieldCode="AU" term="%22Ferro+Desideri+L%22">Ferro Desideri L</searchLink>; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sim+PY%22">Sim PY</searchLink>; Moorfields Eye Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Bernardi+E%22">Bernardi E</searchLink>; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland.<br /><searchLink fieldCode="AU" term="%22Paschon+K%22">Paschon K</searchLink>; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland.<br /><searchLink fieldCode="AU" term="%22Roth+J%22">Roth J</searchLink>; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fung+AT%22">Fung AT</searchLink>; Westmead and Central (Save Sight Institute) Clinical Schools, Specialty of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, Australia; Department of Ophthalmology, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Wu+XN%22">Wu XN</searchLink>; Department of Ophthalmology, Fremantle Hospital, Perth, Australia.<br /><searchLink fieldCode="AU" term="%22Chou+HD%22">Chou HD</searchLink>; Department of Ophthalmology, Chang Gung Memorial Hospital, Linkou Medical Center, Taiwan and College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Henderson+R%22">Henderson R</searchLink>; Moorfields Eye Hospital NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Tsui+E%22">Tsui E</searchLink>; UCLA Stein Eye Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Berrocal+M%22">Berrocal M</searchLink>; Berrocal & Associates, Department of Ophthalmology, University of Puerto Rico, San Juan, Puerto Rico, USA.<br /><searchLink fieldCode="AU" term="%22Chhablani+J%22">Chhablani J</searchLink>; Medical Retina and Vitreoretinal Surgery, University of Pittsburgh School of Medicine, Pittsburg, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wykoff+CC%22">Wykoff CC</searchLink>; Retina Consultants of Texas; Blanton Eye Institute Houston Methodist Hospital, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Cheung+CMG%22">Cheung CMG</searchLink>; Singapore National Eye Centre, Singapore; Singapore Eye Research Institute, Singapore; Eye-ACP, Duke-NUS Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Querques+G%22">Querques G</searchLink>; Department of Ophthalmology, University Vita-Salute IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Melo+GB%22">Melo GB</searchLink>; Federal University of São Paulo, UNIFESP, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Subhi+Y%22">Subhi Y</searchLink>; Department of Ophthalmology, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Loewenstein+A%22">Loewenstein A</searchLink>; Department of Ophthalmology, Tel Aviv Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Kiilgaard+JF%22">Kiilgaard JF</searchLink>; Department of Ophthalmology, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Zinkernagel+M%22">Zinkernagel M</searchLink>; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Department for BioMedical Research, University of Bern, Murtenstrasse 24, Bern CH-3008, Switzerland.<br /><searchLink fieldCode="AU" term="%22Anguita+R%22">Anguita R</searchLink>; Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Freiburgstrasse 15, Bern CH-3010, Switzerland; Moorfields Eye Hospital NHS Foundation Trust, London, UK. Electronic address: rodrigoanguita@gmail.com.
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