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Optimizing the detection of N-nitrosamine mutagenicity in the Ames test.

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Title: Optimizing the detection of N-nitrosamine mutagenicity in the Ames test.
Authors: Heflich RH; U.S. Food and Drug Administration, National Center for Toxicological Research, USA. Electronic address: robert.heflich@fda.hhs.gov., Bishop ME; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Mittelstaedt RA; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Yan J; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Guerrero SK; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Sims AM; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Mitchell K; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Moore N; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Li X; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Mei N; U.S. Food and Drug Administration, National Center for Toxicological Research, USA., Elespuru RK; U.S Food and Drug Administration, USA., King ST; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Generic Drugs, USA., Keire DA; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Quality, USA., Kruhlak NL; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Translational Sciences, USA., Dorsam RT; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Generic Drugs, USA., Raw AS; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Quality, USA., Davis Bruno KL; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA., McGovern TJ; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA., Atrakchi AH; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA.
Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2024 Nov; Vol. 153, pp. 105709. Date of Electronic Publication: 2024 Sep 28.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE
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  Data: Optimizing the detection of N-nitrosamine mutagenicity in the Ames test.
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  Data: <searchLink fieldCode="AU" term="%22Heflich+RH%22">Heflich RH</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA. Electronic address: robert.heflich@fda.hhs.gov.<br /><searchLink fieldCode="AU" term="%22Bishop+ME%22">Bishop ME</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Mittelstaedt+RA%22">Mittelstaedt RA</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Yan+J%22">Yan J</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Guerrero+SK%22">Guerrero SK</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Sims+AM%22">Sims AM</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Mitchell+K%22">Mitchell K</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Moore+N%22">Moore N</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Mei+N%22">Mei N</searchLink>; U.S. Food and Drug Administration, National Center for Toxicological Research, USA.<br /><searchLink fieldCode="AU" term="%22Elespuru+RK%22">Elespuru RK</searchLink>; U.S Food and Drug Administration, USA.<br /><searchLink fieldCode="AU" term="%22King+ST%22">King ST</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Generic Drugs, USA.<br /><searchLink fieldCode="AU" term="%22Keire+DA%22">Keire DA</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Quality, USA.<br /><searchLink fieldCode="AU" term="%22Kruhlak+NL%22">Kruhlak NL</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Translational Sciences, USA.<br /><searchLink fieldCode="AU" term="%22Dorsam+RT%22">Dorsam RT</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Generic Drugs, USA.<br /><searchLink fieldCode="AU" term="%22Raw+AS%22">Raw AS</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of Pharmaceutical Quality, USA.<br /><searchLink fieldCode="AU" term="%22Davis+Bruno+KL%22">Davis Bruno KL</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA.<br /><searchLink fieldCode="AU" term="%22McGovern+TJ%22">McGovern TJ</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA.<br /><searchLink fieldCode="AU" term="%22Atrakchi+AH%22">Atrakchi AH</searchLink>; U.S. Food and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, USA.
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