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Stereochemical optimization of N,2-substituted cycloalkylamines as norepinephrine reuptake inhibitors.

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Title: Stereochemical optimization of N,2-substituted cycloalkylamines as norepinephrine reuptake inhibitors.
Authors: Dilweg MA; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl., Mocking TAM; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl., Maragkoudakis P; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl., van Westen GJP; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl., Heitman LH; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.; Oncode Institute 2333 CC Leiden The Netherlands., IJzerman AP; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl., Jespers W; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl., van der Es D; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.
Source: RSC medicinal chemistry [RSC Med Chem] 2024 Sep 12. Date of Electronic Publication: 2024 Sep 12.
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem
Database: MEDLINE Ultimate
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  Data: Stereochemical optimization of N,2-substituted cycloalkylamines as norepinephrine reuptake inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Dilweg+MA%22">Dilweg MA</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.<br /><searchLink fieldCode="AU" term="%22Mocking+TAM%22">Mocking TAM</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.<br /><searchLink fieldCode="AU" term="%22Maragkoudakis+P%22">Maragkoudakis P</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.<br /><searchLink fieldCode="AU" term="%22van+Westen+GJP%22">van Westen GJP</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.<br /><searchLink fieldCode="AU" term="%22Heitman+LH%22">Heitman LH</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.; Oncode Institute 2333 CC Leiden The Netherlands.<br /><searchLink fieldCode="AU" term="%22IJzerman+AP%22">IJzerman AP</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.<br /><searchLink fieldCode="AU" term="%22Jespers+W%22">Jespers W</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.<br /><searchLink fieldCode="AU" term="%22van+der+Es+D%22">van der Es D</searchLink>; Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research, Leiden University Einsteinweg 55 2333 CC Leiden The Netherlands d.van.der.es@lacdr.leidenuniv.nl.
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        Value: 10.1039/d4md00521j
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              Text: 2024 Sep 12
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