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The epigenetic state of the cell of origin defines mechanisms of leukemogenesis.

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Title: The epigenetic state of the cell of origin defines mechanisms of leukemogenesis.
Authors: Li Z; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Children's Hospital of Soochow University, Suzhou, Jiangsu, China., Fierstein S; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Tanaka-Yano M; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Frenis K; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Chen CC; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Wang D; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Falchetti M; Federal University of Santa Catarina, Florianopolis, Brazil., Côté P; Massachusetts Institute of Technology, Cambridge, MA, USA., Curran C; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Lu K; Massachusetts Institute of Technology, Cambridge, MA, USA., Liu T; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA., Orkin S; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Li H; Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Pediatrics, University of California, San Diego, CA, USA., Lummertz da Rocha E; Federal University of Santa Catarina, Florianopolis, Brazil., Hu S; Department of Hematology/Oncology, Children's Hospital of Soochow University, Suzhou, Jiangsu, China. hushaoyan@suda.edu.cn., Zhu Q; Baylor College of Medicine, Department of Molecular and Human Genetics, Houston, TX, USA. qian.zhu@bcm.edu., Rowe RG; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA. Grant_rowe@dfci.harvard.edu.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. Grant_rowe@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. Grant_rowe@dfci.harvard.edu.
Source: Leukemia [Leukemia] 2025 Jan; Vol. 39 (1), pp. 87-97. Date of Electronic Publication: 2024 Oct 01.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The epigenetic state of the cell of origin defines mechanisms of leukemogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Children's Hospital of Soochow University, Suzhou, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Fierstein+S%22">Fierstein S</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tanaka-Yano+M%22">Tanaka-Yano M</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Frenis+K%22">Frenis K</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+CC%22">Chen CC</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Falchetti+M%22">Falchetti M</searchLink>; Federal University of Santa Catarina, Florianopolis, Brazil.<br /><searchLink fieldCode="AU" term="%22Côté+P%22">Côté P</searchLink>; Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Curran+C%22">Curran C</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lu+K%22">Lu K</searchLink>; Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+T%22">Liu T</searchLink>; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Orkin+S%22">Orkin S</searchLink>; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Pediatrics, University of California, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lummertz+da+Rocha+E%22">Lummertz da Rocha E</searchLink>; Federal University of Santa Catarina, Florianopolis, Brazil.<br /><searchLink fieldCode="AU" term="%22Hu+S%22">Hu S</searchLink>; Department of Hematology/Oncology, Children's Hospital of Soochow University, Suzhou, Jiangsu, China. hushaoyan@suda.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhu+Q%22">Zhu Q</searchLink>; Baylor College of Medicine, Department of Molecular and Human Genetics, Houston, TX, USA. qian.zhu@bcm.edu.<br /><searchLink fieldCode="AU" term="%22Rowe+RG%22">Rowe RG</searchLink>; Stem Cell Program and Stem Cell Transplantation Programs, Boston Children's Hospital, Boston, MA, USA. Grant_rowe@dfci.harvard.edu.; Department of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. Grant_rowe@dfci.harvard.edu.; Harvard Medical School, Boston, MA, USA. Grant_rowe@dfci.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2025 Jan; Vol. 39 (1), pp. 87-97. <i>Date of Electronic Publication: </i>2024 Oct 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%2C+Specialist+Journals%22">Nature Publishing Group, Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8704895 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5551 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208876924%22">08876924 </searchLink><i>NLM ISO Abbreviation: </i>Leukemia <i>Subsets: </i>MEDLINE
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