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Effect of add-on naldemedine treatment in patients with cancer and opioid-induced constipation insufficiently responding to magnesium oxide: a pooled, subgroup analysis of two randomized controlled trials.

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Title: Effect of add-on naldemedine treatment in patients with cancer and opioid-induced constipation insufficiently responding to magnesium oxide: a pooled, subgroup analysis of two randomized controlled trials.
Authors: Kessoku T; Department of Palliative Medicine and Gastroenterology, International University of Health and Welfare Narita Hospital, Narita, Chiba, Japan.; Department of Gastroenterology, International University of Health and Welfare Graduate School of Medicine, Narita, Chiba, Japan.; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Akamatsu T; Medical Affairs Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan., Morioka Y; Medical Affairs Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan., Yokota T; Clinical Research Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan., Kobayashi M; Data Science Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan., Uchida K; Business System Department, INFRONT Inc., Osaka, Japan., Koretaka Y; Data Science Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan., Nakajima A; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Source: Japanese journal of clinical oncology [Jpn J Clin Oncol] 2025 Jan 08; Vol. 55 (1), pp. 40-48.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase II; Clinical Trial, Phase III
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0313225 Publication Model: Print Cited Medium: Internet ISSN: 1465-3621 (Electronic) Linking ISSN: 03682811 NLM ISO Abbreviation: Jpn J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Effect of add-on naldemedine treatment in patients with cancer and opioid-induced constipation insufficiently responding to magnesium oxide: a pooled, subgroup analysis of two randomized controlled trials.
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  Data: <searchLink fieldCode="AU" term="%22Kessoku+T%22">Kessoku T</searchLink>; Department of Palliative Medicine and Gastroenterology, International University of Health and Welfare Narita Hospital, Narita, Chiba, Japan.; Department of Gastroenterology, International University of Health and Welfare Graduate School of Medicine, Narita, Chiba, Japan.; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Akamatsu+T%22">Akamatsu T</searchLink>; Medical Affairs Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Morioka+Y%22">Morioka Y</searchLink>; Medical Affairs Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Yokota+T%22">Yokota T</searchLink>; Clinical Research Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Kobayashi+M%22">Kobayashi M</searchLink>; Data Science Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Uchida+K%22">Uchida K</searchLink>; Business System Department, INFRONT Inc., Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Koretaka+Y%22">Koretaka Y</searchLink>; Data Science Department, Shionogi & Co., Ltd, Chuo-ku, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Nakajima+A%22">Nakajima A</searchLink>; Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0313225 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1465-3621 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203682811%22">03682811 </searchLink><i>NLM ISO Abbreviation: </i>Jpn J Clin Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1093/jjco/hyae135
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        Text: English
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      – TitleFull: Effect of add-on naldemedine treatment in patients with cancer and opioid-induced constipation insufficiently responding to magnesium oxide: a pooled, subgroup analysis of two randomized controlled trials.
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            – D: 08
              M: 01
              Text: 2025 Jan 08
              Type: published
              Y: 2025
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