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Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes.

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Title: Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes.
Authors: Brinkkemper M; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Kerster G; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Brouwer PJM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Tran AS; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Torres JL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Ettema RA; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Nijhuis H; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Allen JD; School of Biological Sciences, University of Southampton, Southampton, United Kingdom., Zhu W; School of Biological Sciences, University of Southampton, Southampton, United Kingdom., Gao H; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America., Lee WH; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Bijl TPL; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Snitselaar JL; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Burger JA; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Bontjer I; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Olijhoek W; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Ravichandran R; Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.; Institute for Protein Design, University of Washington, Seattle, Washington, United States of America., van Breemen MJ; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Del Moral-Sánchez I; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Derking R; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Sliepen K; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Ozorowski G; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., Crispin M; School of Biological Sciences, University of Southampton, Southampton, United Kingdom., Montefiori DC; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America., Claireaux M; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America., van Gils MJ; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands., King NP; Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.; Institute for Protein Design, University of Washington, Seattle, Washington, United States of America., Sanders RW; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America.
Source: PLoS pathogens [PLoS Pathog] 2024 Oct 03; Vol. 20 (10), pp. e1012558. Date of Electronic Publication: 2024 Oct 03 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mosaic and mixed HIV-1 glycoprotein nanoparticles elicit antibody responses to broadly neutralizing epitopes.
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Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Ettema+RA%22">Ettema RA</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Nijhuis+H%22">Nijhuis H</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Allen+JD%22">Allen JD</searchLink>; School of Biological Sciences, University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Zhu+W%22">Zhu W</searchLink>; 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Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.; Institute for Protein Design, University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22van+Breemen+MJ%22">van Breemen MJ</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Del+Moral-Sánchez+I%22">Del Moral-Sánchez I</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Derking+R%22">Derking R</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Sliepen+K%22">Sliepen K</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ozorowski+G%22">Ozorowski G</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Crispin+M%22">Crispin M</searchLink>; School of Biological Sciences, University of Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Montefiori+DC%22">Montefiori DC</searchLink>; Duke Human Vaccine Institute and Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Claireaux+M%22">Claireaux M</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22King+NP%22">King NP</searchLink>; Department of Biochemistry, University of Washington, Seattle, Washington, United States of America.; Institute for Protein Design, University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Sanders+RW%22">Sanders RW</searchLink>; Amsterdam UMC, location University of Amsterdam, Department of Medical Microbiology and Infection prevention, Amsterdam, The Netherlands.; Amsterdam institute for Infection and Immunity, Infectious diseases, Amsterdam, The Netherlands.; Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, New York, United States of America.
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