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Genetic architecture reconciles linkage and association studies of complex traits.

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Title: Genetic architecture reconciles linkage and association studies of complex traits.
Authors: Sidorenko J; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. j.sidorenko@imb.uq.edu.au., Couvy-Duchesne B; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Sorbonne University, Paris Brain Institute-ICM, CNRS, INRIA, INSERM, AP-HP, Hôpital de la Pitié Salpêtrière, Paris, France., Kemper KE; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Moen GH; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; The Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia., Bhatta L; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Åsvold BO; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway.; Department of Endocrinology, Clinic of Medicine, St Olavs Hospital, Trondheim, Norway., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Ani A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan, Iran., Wang R; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Nolte IM; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Gordon S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Hayward C; MRC Human Genetics Unit, Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Campbell A; Centre for Genomic and Experimental Medicine, Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Benjamin DJ; Human Genetics Department, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Behavioral Decision Making Group, Anderson School of Management, University of California Los Angeles, Los Angeles, CA, USA.; National Bureau of Economic Research, Cambridge, MA, USA., Cesarini D; National Bureau of Economic Research, Cambridge, MA, USA.; Department of Economics, New York University, New York, NY, USA.; Center for Experimental Social Science, New York University, New York, NY, USA., Evans DM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.; The Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Goddard ME; Centre for AgriBioscience, Agriculture Victoria, Bundoora, Victoria, Australia.; Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia., Haley CS; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK.; Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, UK.; Coupland Craft Cider, Coupland, Northumberland, UK., Porteous D; MRC Human Genetics Unit, Institute of Genetics & Cancer, University of Edinburgh, Western General Hospital, Edinburgh, UK., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway., Brumpton B; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway., Visscher PM; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. peter.visscher@uq.edu.au.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Population Health, University of Oxford, Oxford, UK. peter.visscher@uq.edu.au., Yengo L; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia. l.yengo@imb.uq.edu.au.
Corporate Authors: Estonian Biobank Research Team, Lifelines Cohort Study
Source: Nature genetics [Nat Genet] 2024 Nov; Vol. 56 (11), pp. 2352-2360. Date of Electronic Publication: 2024 Oct 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
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