CASPER: A Phase I trial combining calaspargase pegol-mnkl and cobimetinib in pancreatic cancer.

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Title: CASPER: A Phase I trial combining calaspargase pegol-mnkl and cobimetinib in pancreatic cancer.
Authors: Lopez CD; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland., Kardosh A; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland., Chen EY; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Pegna G; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Guimaraes A; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Radiology, OHSU, OR 97239, Portland., Foster B; Department of Pathology, OHSU, OR 97239, Portland., Brinkerhoff B; Department of Pathology, OHSU, OR 97239, Portland., Goodyear SM; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland., Lim JY; Biostatistics Shared Resource, Knight Cancer Institute (OHSU)., Taber E; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Rajagopalan B; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Edmerson E; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Vo J; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Nelson K; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Jackson A; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Gingerich T; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Fahlman A; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Lessenich C; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Fennell F; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Ventura D; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Roy P; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland., Keith D; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland., Sheppard B; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Surgery, OHSU, OR 97239, Portland., Brody JR; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Surgery, OHSU, OR 97239, Portland., Mills GB; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Precision Oncology, Knight Cancer Institute OHSU, OR 97239, Portland., Ronai ZA; Sanford Burnham Prebys, La Jolla, CA 92037, San Diego., Sears RC; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Molecular and Medical Genetics, OHSU, OR 97239, Portland.
Source: Future oncology (London, England) [Future Oncol] 2024; Vol. 20 (37), pp. 2915-2925. Date of Electronic Publication: 2024 Oct 08.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101256629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-8301 (Electronic) Linking ISSN: 14796694 NLM ISO Abbreviation: Future Oncol Subsets: MEDLINE
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  Data: CASPER: A Phase I trial combining calaspargase pegol-mnkl and cobimetinib in pancreatic cancer.
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  Data: <searchLink fieldCode="AU" term="%22Lopez+CD%22">Lopez CD</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.<br /><searchLink fieldCode="AU" term="%22Kardosh+A%22">Kardosh A</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.<br /><searchLink fieldCode="AU" term="%22Chen+EY%22">Chen EY</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Pegna+G%22">Pegna G</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Guimaraes+A%22">Guimaraes A</searchLink>; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Radiology, OHSU, OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Foster+B%22">Foster B</searchLink>; Department of Pathology, OHSU, OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Brinkerhoff+B%22">Brinkerhoff B</searchLink>; Department of Pathology, OHSU, OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Goodyear+SM%22">Goodyear SM</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.<br /><searchLink fieldCode="AU" term="%22Lim+JY%22">Lim JY</searchLink>; Biostatistics Shared Resource, Knight Cancer Institute (OHSU).<br /><searchLink fieldCode="AU" term="%22Taber+E%22">Taber E</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Rajagopalan+B%22">Rajagopalan B</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Edmerson+E%22">Edmerson E</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Vo+J%22">Vo J</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Nelson+K%22">Nelson K</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Jackson+A%22">Jackson A</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Gingerich+T%22">Gingerich T</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Fahlman+A%22">Fahlman A</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Lessenich+C%22">Lessenich C</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Fennell+F%22">Fennell F</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Ventura+D%22">Ventura D</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Roy+P%22">Roy P</searchLink>; Department of Medicine, Hematology and Medical Oncology, Oregon Health & Science University (OHSU), OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Keith+D%22">Keith D</searchLink>; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.<br /><searchLink fieldCode="AU" term="%22Sheppard+B%22">Sheppard B</searchLink>; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Surgery, OHSU, OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Brody+JR%22">Brody JR</searchLink>; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Surgery, OHSU, OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Mills+GB%22">Mills GB</searchLink>; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Precision Oncology, Knight Cancer Institute OHSU, OR 97239, Portland.<br /><searchLink fieldCode="AU" term="%22Ronai+ZA%22">Ronai ZA</searchLink>; Sanford Burnham Prebys, La Jolla, CA 92037, San Diego.<br /><searchLink fieldCode="AU" term="%22Sears+RC%22">Sears RC</searchLink>; Brenden-Colson Center for Pancreatic Care, Knight Cancer Institute (OHSU), OR, Portland.; Department of Molecular and Medical Genetics, OHSU, OR 97239, Portland.
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  Data: <searchLink fieldCode="JN" term="%22101256629%22">Future oncology (London, England)</searchLink> [Future Oncol] 2024; Vol. 20 (37), pp. 2915-2925. <i>Date of Electronic Publication: </i>2024 Oct 08.
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