Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma.
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| Title: | Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma. |
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| Authors: | Gallitto M; Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA.; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Zhang X; Department of Genetics and Development, Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, New York, USA., De Los Santos G; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Wei HJ; Fralin Biomedical Research Institute, Virginia Polytechnic Institute and State University, Roanoke, 24016, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA.; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Fernández EC; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.; Department of Systems Biology, Columbia University Irving Medical Center, New York, New York, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA., Duan S; Department of Genetics and Development, Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, New York, USA.; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China., Sedor G; Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA.; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Yoh N; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, New York, USA., Kokossis D; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Angel JC; Department of Molecular Pharmacology and Therapeutics, Columbia University, New York, New York, USA.; Department of Biomedical Informatics, Columbia University, New York, New York, USA., Wang YF; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., White E; Department of Systems Biology, Columbia University Irving Medical Center, New York, New York, USA., Kinslow CJ; Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA.; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Berg X; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Tomassoni L; Department of Systems Biology, Columbia University Irving Medical Center, New York, New York, USA.; DarwinHealth Inc., New York, NYUSA., Zandkarimi F; Department of Chemistry, Columbia University, New York, New York, USA., Chio IIC; Department of Genetics and Development, Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, New York, USA., Canoll P; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, New York, USA.; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, New York, USA., Bruce JN; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, New York, USA., Feldstein NA; Department of Neurological Surgery, Columbia University Irving Medical Center, New York, New York, USA., Gartrell RD; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA.; Division of Pediatric Oncology, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Cheng SK; Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA.; Department of Radiation Oncology, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Garvin JH; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA., Zacharoulis S; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA., Wechsler-Reya RJ; Department of Neurology, Columbia University Irving Medical Center, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Pavisic J; Department of Pediatrics, Columbia University Irving Medical Center, New York, New York, USA.; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Califano A; Chan Zuckerberg Biohub New York, New York, New York, USA.; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, USA.; Department of Medicine, Columbia University, New York, New YorkUSA.; Department of Biomedical Informatics, Columbia University, New York, New York, USA.; Department of Systems Biology, Columbia University Irving Medical Center, New York, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian, New York, New York, USA., Zhang Z; Department of Genetics and Development, Institute for Cancer Genetics, Columbia University Irving Medical Center, New York, New York, USA., Wu CC; Fralin Biomedical Research Institute, Virginia Polytechnic Institute and State University, Roanoke, 24016, USA.; Department of Internal Medicine, Virginia Tech Carilion School of Medicine, Roanoke, 24016, USA.; Department of Biomedical Engineering and Mechanics, Virginia Polytechnic Institute and State University, Blacksburg, 24061, USA.; The Brain Tumor Institute, Children's National Hospital, Washington, 20010, USA.; Center for Cancer and Immunology Research, Children's National Hospital, Washington, 20010, USA. |
| Source: | Neuro-oncology [Neuro Oncol] 2025 Mar 07; Vol. 27 (3), pp. 795-810. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1523-5866 |
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| DOI: | 10.1093/neuonc/noae215 |
