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Anti-OAcGD2 antibody in combination with ceramide kinase inhibitor mediates potent antitumor cytotoxicity against breast cancer and diffuse intrinsic pontine glioma cells.

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Title: Anti-OAcGD2 antibody in combination with ceramide kinase inhibitor mediates potent antitumor cytotoxicity against breast cancer and diffuse intrinsic pontine glioma cells.
Authors: Kasprowicz A; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France.; OGD2Pharma, Institut de Recherche en Santé IRS2 - Nantes Biotech, Boulevard Benoni Goullin, 44200, Nantes, France., Cavdarli S; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France., Delannoy P; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France., Le Guezennec X; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore., Defebvre C; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, 59000, Lille, France., Spriet C; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, 59000, Lille, France., Jonckheere N; Univ Lille, CNRS, Inserm, CHU Lille, Institut de Recherche Contre Le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther Cancer Heterogeneity, Plasticity and Resistance to Therapies, 59000, Lille, France., Le Doussal JM; OGD2Pharma, Institut de Recherche en Santé IRS2 - Nantes Biotech, Boulevard Benoni Goullin, 44200, Nantes, France., Krzewinski-Recchi MA; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France., Mitra S; Univ Lille, CNRS, Inserm, CHU Lille, Institut de Recherche Contre Le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther Cancer Heterogeneity, Plasticity and Resistance to Therapies, 59000, Lille, France., Meignan S; Univ Lille, CNRS, Inserm, CHU Lille, Institut de Recherche Contre Le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther Cancer Heterogeneity, Plasticity and Resistance to Therapies, 59000, Lille, France.; Tumorigenesis and Resistance to Treatment Unit, Centre Oscar Lambret, 59000, Lille, France., Groux-Degroote S; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France. sophie.groux-degroote@univ-lille.fr.
Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2025 Apr; Vol. 480 (4), pp. 2555-2571. Date of Electronic Publication: 2024 Oct 12.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Anti-OAcGD2 antibody in combination with ceramide kinase inhibitor mediates potent antitumor cytotoxicity against breast cancer and diffuse intrinsic pontine glioma cells.
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  Data: <searchLink fieldCode="AU" term="%22Kasprowicz+A%22">Kasprowicz A</searchLink>; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France.; OGD2Pharma, Institut de Recherche en Santé IRS2 - Nantes Biotech, Boulevard Benoni Goullin, 44200, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Cavdarli+S%22">Cavdarli S</searchLink>; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France.<br /><searchLink fieldCode="AU" term="%22Delannoy+P%22">Delannoy P</searchLink>; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France.<br /><searchLink fieldCode="AU" term="%22Le+Guezennec+X%22">Le Guezennec X</searchLink>; Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Defebvre+C%22">Defebvre C</searchLink>; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, 59000, Lille, France.<br /><searchLink fieldCode="AU" term="%22Spriet+C%22">Spriet C</searchLink>; Univ. Lille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, US 41 - UAR 2014 - PLBS, 59000, Lille, France.<br /><searchLink fieldCode="AU" term="%22Jonckheere+N%22">Jonckheere N</searchLink>; Univ Lille, CNRS, Inserm, CHU Lille, Institut de Recherche Contre Le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther Cancer Heterogeneity, Plasticity and Resistance to Therapies, 59000, Lille, France.<br /><searchLink fieldCode="AU" term="%22Le+Doussal+JM%22">Le Doussal JM</searchLink>; OGD2Pharma, Institut de Recherche en Santé IRS2 - Nantes Biotech, Boulevard Benoni Goullin, 44200, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Krzewinski-Recchi+MA%22">Krzewinski-Recchi MA</searchLink>; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France.<br /><searchLink fieldCode="AU" term="%22Mitra+S%22">Mitra S</searchLink>; Univ Lille, CNRS, Inserm, CHU Lille, Institut de Recherche Contre Le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther Cancer Heterogeneity, Plasticity and Resistance to Therapies, 59000, Lille, France.<br /><searchLink fieldCode="AU" term="%22Meignan+S%22">Meignan S</searchLink>; Univ Lille, CNRS, Inserm, CHU Lille, Institut de Recherche Contre Le Cancer de Lille, UMR9020 - UMR-S 1277 - Canther Cancer Heterogeneity, Plasticity and Resistance to Therapies, 59000, Lille, France.; Tumorigenesis and Resistance to Treatment Unit, Centre Oscar Lambret, 59000, Lille, France.<br /><searchLink fieldCode="AU" term="%22Groux-Degroote+S%22">Groux-Degroote S</searchLink>; Univ Lille, CNRS, UMR 8576 - UGSF - Unité de Glycosbiologie Structurale et Fonctionnelle, 59655, Villeneuve d'Ascq, France. sophie.groux-degroote@univ-lille.fr.
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