Addressing the Generalizability of AI in Radiology Using a Novel Data Augmentation Framework with Synthetic Patient Image Data: Proof-of-Concept and External Validation for Classification Tasks in Multiple Sclerosis.

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Title: Addressing the Generalizability of AI in Radiology Using a Novel Data Augmentation Framework with Synthetic Patient Image Data: Proof-of-Concept and External Validation for Classification Tasks in Multiple Sclerosis.
Authors: Brugnara G; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Jayachandran Preetha C; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Deike K; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Haase R; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Pinetz T; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Foltyn-Dumitru M; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Mahmutoglu MA; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Wildemann B; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Diem R; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Wick W; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Radbruch A; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Bendszus M; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Meredig H; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Rastogi A; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.)., Vollmuth P; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).
Source: Radiology. Artificial intelligence [Radiol Artif Intell] 2024 Nov; Vol. 6 (6), pp. e230514.
Publication Type: Journal Article; Validation Study; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Radiological Society of North America, Inc Country of Publication: United States NLM ID: 101746556 Publication Model: Print Cited Medium: Internet ISSN: 2638-6100 (Electronic) Linking ISSN: 26386100 NLM ISO Abbreviation: Radiol Artif Intell Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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Items – Name: Title
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  Data: Addressing the Generalizability of AI in Radiology Using a Novel Data Augmentation Framework with Synthetic Patient Image Data: Proof-of-Concept and External Validation for Classification Tasks in Multiple Sclerosis.
– Name: Author
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  Data: <searchLink fieldCode="AU" term="%22Brugnara+G%22">Brugnara G</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Jayachandran+Preetha+C%22">Jayachandran Preetha C</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Deike+K%22">Deike K</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Haase+R%22">Haase R</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Pinetz+T%22">Pinetz T</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Foltyn-Dumitru+M%22">Foltyn-Dumitru M</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Mahmutoglu+MA%22">Mahmutoglu MA</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Wildemann+B%22">Wildemann B</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Diem+R%22">Diem R</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Wick+W%22">Wick W</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Radbruch+A%22">Radbruch A</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Bendszus+M%22">Bendszus M</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Meredig+H%22">Meredig H</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Rastogi+A%22">Rastogi A</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).<br /><searchLink fieldCode="AU" term="%22Vollmuth+P%22">Vollmuth P</searchLink>; From the Department of Neuroradiology (G.B., C.J.P., M.F.D., M.A.M., M.B., H.M., A. Rastogi, P.V.), Division for Computational Neuroimaging (G.B., C.J.P., M.F.D., M.A.M., H.M., A. Rastogi, P.V.), and Department of Neurology (B.W., R.D., W.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Neuroradiology (G.B., K.D., R.H., M.F.D., A. Radbruch, P.V.), Division for Computational Radiology and Clinical AI (G.B., M.F.D., A. Radbruch, P.V.), Bonn University Hospital, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (K.D., A. Radbruch); Division of Medical Image Computing, German Cancer Research Center (DKFZ), Heidelberg, Germany (G.B., P.V.); and Institute for Applied Mathematics, University of Bonn, Bonn, Germany (T.P.).
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  Data: <searchLink fieldCode="JN" term="%22101746556%22">Radiology. Artificial intelligence</searchLink> [Radiol Artif Intell] 2024 Nov; Vol. 6 (6), pp. e230514.
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  Data: Journal Article; Validation Study; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Radiological+Society+of+North+America%2C+Inc%22">Radiological Society of North America, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101746556 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2638-6100 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226386100%22">26386100 </searchLink><i>NLM ISO Abbreviation: </i>Radiol Artif Intell <i>Subsets: </i>MEDLINE
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        Value: 10.1148/ryai.230514
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      – Code: eng
        Text: English
    PhysicalDescription:
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        StartPage: e230514
    Titles:
      – TitleFull: Addressing the Generalizability of AI in Radiology Using a Novel Data Augmentation Framework with Synthetic Patient Image Data: Proof-of-Concept and External Validation for Classification Tasks in Multiple Sclerosis.
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            – D: 01
              M: 11
              Text: 2024 Nov
              Type: published
              Y: 2024
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            – TitleFull: Radiology. Artificial intelligence
              Type: main
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