A multiantigenic Orf virus-based vaccine efficiently protects hamsters and nonhuman primates against SARS-CoV-2.

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Title: A multiantigenic Orf virus-based vaccine efficiently protects hamsters and nonhuman primates against SARS-CoV-2.
Authors: Reguzova A; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Müller M; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Pagallies F; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Burri D; Speransa Therapeutics, Bethmannstrasse 8, 60311, Frankfurt am Main, Germany., Salomon F; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Rziha HJ; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Bittner-Schrader Z; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany., Verstrepen BE; Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288GJ, Rijswijk, The Netherlands.; Department of Viroscience, Erasmus University Medical Center, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands., Böszörményi KP; Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288GJ, Rijswijk, The Netherlands., Verschoor EJ; Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288GJ, Rijswijk, The Netherlands., Gerhauser I; Department of Pathology, University of Veterinary Medicine Hannover Foundation, Bünteweg 17, 30559, Hannover, Germany., Elbers K; Boehringer Ingelheim International GmbH, Binger Strasse 173, 55216, Ingelheim am Rhein, Germany.; ViraTherapeutics GmbH, Bundesstraße 27, 6063, Rum, Austria., Esen M; Institute of Tropical Medicine, University of Tübingen, Wilhelmstraße 27, 72074, Tübingen, Germany.; German Center for Infection Research (DZIF), Partner Site Tübingen; Cluster of Excellence (EXC2124) 'Controlling Microbes to Fight Infection', Tübingen, Germany., Manenti A; VisMederi Srl., Strada del Petriccio e Belriguardo 35, 53100, Siena, Italy., Monti M; VisMederi Srl., Strada del Petriccio e Belriguardo 35, 53100, Siena, Italy., Rammensee HG; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany., Derouazi M; Speransa Therapeutics, Bethmannstrasse 8, 60311, Frankfurt am Main, Germany., Löffler MW; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany. markus.loeffler@uni-tuebingen.de.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany. markus.loeffler@uni-tuebingen.de.; Institute for Clinical and Experimental Transfusion Medicine, Medical Faculty of Tübingen, University Hospital Tübingen, Otfried-Müller-Str. 4/1, 72076, Tübingen, Germany. markus.loeffler@uni-tuebingen.de.; Centre for Clinical Transfusion Medicine, Otfried-Müller-Str. 4/1, 72076, Tübingen, Germany. markus.loeffler@uni-tuebingen.de., Amann R; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany. ralf.amann@ifiz.uni-tuebingen.de.
Source: NPJ vaccines [NPJ Vaccines] 2024 Oct 16; Vol. 9 (1), pp. 191. Date of Electronic Publication: 2024 Oct 16.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature in partnership with the Sealy Center for Vaccine Development Country of Publication: England NLM ID: 101699863 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-0105 (Electronic) Linking ISSN: 20590105 NLM ISO Abbreviation: NPJ Vaccines Subsets: PubMed not MEDLINE
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  Data: A multiantigenic Orf virus-based vaccine efficiently protects hamsters and nonhuman primates against SARS-CoV-2.
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  Data: <searchLink fieldCode="AU" term="%22Reguzova+A%22">Reguzova A</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+M%22">Müller M</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Pagallies+F%22">Pagallies F</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Burri+D%22">Burri D</searchLink>; Speransa Therapeutics, Bethmannstrasse 8, 60311, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Salomon+F%22">Salomon F</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Rziha+HJ%22">Rziha HJ</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Bittner-Schrader+Z%22">Bittner-Schrader Z</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Verstrepen+BE%22">Verstrepen BE</searchLink>; Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288GJ, Rijswijk, The Netherlands.; Department of Viroscience, Erasmus University Medical Center, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Böszörményi+KP%22">Böszörményi KP</searchLink>; Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288GJ, Rijswijk, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verschoor+EJ%22">Verschoor EJ</searchLink>; Department of Virology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288GJ, Rijswijk, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gerhauser+I%22">Gerhauser I</searchLink>; Department of Pathology, University of Veterinary Medicine Hannover Foundation, Bünteweg 17, 30559, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Elbers+K%22">Elbers K</searchLink>; Boehringer Ingelheim International GmbH, Binger Strasse 173, 55216, Ingelheim am Rhein, Germany.; ViraTherapeutics GmbH, Bundesstraße 27, 6063, Rum, Austria.<br /><searchLink fieldCode="AU" term="%22Esen+M%22">Esen M</searchLink>; Institute of Tropical Medicine, University of Tübingen, Wilhelmstraße 27, 72074, Tübingen, Germany.; German Center for Infection Research (DZIF), Partner Site Tübingen; Cluster of Excellence (EXC2124) 'Controlling Microbes to Fight Infection', Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Manenti+A%22">Manenti A</searchLink>; VisMederi Srl., Strada del Petriccio e Belriguardo 35, 53100, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Monti+M%22">Monti M</searchLink>; VisMederi Srl., Strada del Petriccio e Belriguardo 35, 53100, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Rammensee+HG%22">Rammensee HG</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Derouazi+M%22">Derouazi M</searchLink>; Speransa Therapeutics, Bethmannstrasse 8, 60311, Frankfurt am Main, Germany.<br /><searchLink fieldCode="AU" term="%22Löffler+MW%22">Löffler MW</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany. markus.loeffler@uni-tuebingen.de.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies', University of Tübingen, Tübingen, Germany. markus.loeffler@uni-tuebingen.de.; Institute for Clinical and Experimental Transfusion Medicine, Medical Faculty of Tübingen, University Hospital Tübingen, Otfried-Müller-Str. 4/1, 72076, Tübingen, Germany. markus.loeffler@uni-tuebingen.de.; Centre for Clinical Transfusion Medicine, Otfried-Müller-Str. 4/1, 72076, Tübingen, Germany. markus.loeffler@uni-tuebingen.de.<br /><searchLink fieldCode="AU" term="%22Amann+R%22">Amann R</searchLink>; Institute of Immunology, University Hospital Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany. ralf.amann@ifiz.uni-tuebingen.de.
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  Data: <searchLink fieldCode="JN" term="%22101699863%22">NPJ vaccines</searchLink> [NPJ Vaccines] 2024 Oct 16; Vol. 9 (1), pp. 191. <i>Date of Electronic Publication: </i>2024 Oct 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature+in+partnership+with+the+Sealy+Center+for+Vaccine+Development%22">Springer Nature in partnership with the Sealy Center for Vaccine Development </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101699863 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-0105 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220590105%22">20590105 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Vaccines <i>Subsets: </i>PubMed not MEDLINE
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