View in EDS HTML Full Text PDF Full Text

Building Confidence in Physiologically Based Pharmacokinetic Modeling of CYP3A Induction Mediated by Rifampin: An Industry Perspective.

Saved in:
Bibliographic Details
Title: Building Confidence in Physiologically Based Pharmacokinetic Modeling of CYP3A Induction Mediated by Rifampin: An Industry Perspective.
Authors: Reddy MB; Clinical Pharmacology, Oncology, Pfizer Inc., Boulder, Colorado, USA., Cabalu TD; DMPK, Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics, Merck & Co., Inc., Rahway, New Jersey, USA., de Zwart L; DMPK, Janssen Pharmaceutica NV, A Johnson & Johnson Company, Beerse, Belgium., Ramsden D; DMPK, Research and Early Development, Oncology R&D, AstraZeneca, Boston, Massachusetts, USA., Dowty ME; Pharmacokinetics Dynamics and Metabolism, Pfizer Inc, Cambridge, Massachusetts, USA., Taskar KS; DMPK, Pre-Clinical Sciences, Research Technologies, GSK, Stevenage, UK., Badée J; PK Sciences, Biomedical Research, Novartis, Basel, Switzerland., Bolleddula J; Quantitative Pharmacology, EMD Serono Research & Development Institute, Inc., Billerica, Massachusetts, USA., Boulu L; Modeling and Simulation, Translational Medicine and Early Development, Sanofi, Montpellier, France., Fu Q; Modeling and Simulation, Vertex Pharmaceuticals, Boston, Massachusetts, USA., Kotsuma M; Quantitative Clinical Pharmacology, Daiichi Sankyo Co., Ltd., Tokyo, Japan., Leblanc AF; Quantitative, Translational & ADME Sciences, Development Science, AbbVie, North Chicago, Illinois, USA., Lewis G; DMPK, Pre-Clinical Sciences, Research Technologies, GSK, Stevenage, UK., Liang G; DMPK, Vertex Pharmaceuticals, Boston, Massachusetts, USA., Parrott N; Pharmaceutical Sciences, Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland., Pilla Reddy V; Global PKPD/Pharmacometrics, Eli Lilly and Company, Bracknell, UK and Indianapolis, Indiana, USA., Prakash C; DMPK and Clinical Pharmacology, Agios, Cambridge, Massachusetts, USA., Shah K; Quantitative Clinical Pharmacology, Takeda Pharmaceuticals International Inc., Cambridge, Massachusetts, USA., Umehara K; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd., Basel, Switzerland., Mukherjee D; Quantitative Clinical Pharmacology, Daiichi-Sankyo Inc., Basking Ridge, New Jersey, USA., Rehmel J; Global PKPD/Pharmacometrics, Eli Lilly and Company, Bracknell, UK and Indianapolis, Indiana, USA., Hariparsad N; DMPK, Research and Early Development, Oncology R&D, AstraZeneca, Boston, Massachusetts, USA.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Feb; Vol. 117 (2), pp. 403-420. Date of Electronic Publication: 2024 Oct 18.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39422118
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Building Confidence in Physiologically Based Pharmacokinetic Modeling of CYP3A Induction Mediated by Rifampin: An Industry Perspective.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Reddy+MB%22">Reddy MB</searchLink>; Clinical Pharmacology, Oncology, Pfizer Inc., Boulder, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Cabalu+TD%22">Cabalu TD</searchLink>; DMPK, Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics, Merck & Co., Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22de+Zwart+L%22">de Zwart L</searchLink>; DMPK, Janssen Pharmaceutica NV, A Johnson & Johnson Company, Beerse, Belgium.<br /><searchLink fieldCode="AU" term="%22Ramsden+D%22">Ramsden D</searchLink>; DMPK, Research and Early Development, Oncology R&D, AstraZeneca, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Dowty+ME%22">Dowty ME</searchLink>; Pharmacokinetics Dynamics and Metabolism, Pfizer Inc, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Taskar+KS%22">Taskar KS</searchLink>; DMPK, Pre-Clinical Sciences, Research Technologies, GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Badée+J%22">Badée J</searchLink>; PK Sciences, Biomedical Research, Novartis, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bolleddula+J%22">Bolleddula J</searchLink>; Quantitative Pharmacology, EMD Serono Research & Development Institute, Inc., Billerica, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Boulu+L%22">Boulu L</searchLink>; Modeling and Simulation, Translational Medicine and Early Development, Sanofi, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Fu+Q%22">Fu Q</searchLink>; Modeling and Simulation, Vertex Pharmaceuticals, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Kotsuma+M%22">Kotsuma M</searchLink>; Quantitative Clinical Pharmacology, Daiichi Sankyo Co., Ltd., Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Leblanc+AF%22">Leblanc AF</searchLink>; Quantitative, Translational & ADME Sciences, Development Science, AbbVie, North Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+G%22">Lewis G</searchLink>; DMPK, Pre-Clinical Sciences, Research Technologies, GSK, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Liang+G%22">Liang G</searchLink>; DMPK, Vertex Pharmaceuticals, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Parrott+N%22">Parrott N</searchLink>; Pharmaceutical Sciences, Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pilla+Reddy+V%22">Pilla Reddy V</searchLink>; Global PKPD/Pharmacometrics, Eli Lilly and Company, Bracknell, UK and Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Prakash+C%22">Prakash C</searchLink>; DMPK and Clinical Pharmacology, Agios, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Shah+K%22">Shah K</searchLink>; Quantitative Clinical Pharmacology, Takeda Pharmaceuticals International Inc., Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Umehara+K%22">Umehara K</searchLink>; Roche Pharmaceutical Research and Early Development, Roche Innovation Center, F. Hoffmann-La Roche Ltd., Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mukherjee+D%22">Mukherjee D</searchLink>; Quantitative Clinical Pharmacology, Daiichi-Sankyo Inc., Basking Ridge, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Rehmel+J%22">Rehmel J</searchLink>; Global PKPD/Pharmacometrics, Eli Lilly and Company, Bracknell, UK and Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Hariparsad+N%22">Hariparsad N</searchLink>; DMPK, Research and Early Development, Oncology R&D, AstraZeneca, Boston, Massachusetts, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220372741%22">Clinical pharmacology and therapeutics</searchLink> [Clin Pharmacol Ther] 2025 Feb; Vol. 117 (2), pp. 403-420. <i>Date of Electronic Publication: </i>2024 Oct 18.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Review; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372741 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-6535 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200099236%22">00099236 </searchLink><i>NLM ISO Abbreviation: </i>Clin Pharmacol Ther <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39422118
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/cpt.3477
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 403
    Titles:
      – TitleFull: Building Confidence in Physiologically Based Pharmacokinetic Modeling of CYP3A Induction Mediated by Rifampin: An Industry Perspective.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Reddy MB
      – PersonEntity:
          Name:
            NameFull: Cabalu TD
      – PersonEntity:
          Name:
            NameFull: de Zwart L
      – PersonEntity:
          Name:
            NameFull: Ramsden D
      – PersonEntity:
          Name:
            NameFull: Dowty ME
      – PersonEntity:
          Name:
            NameFull: Taskar KS
      – PersonEntity:
          Name:
            NameFull: Badée J
      – PersonEntity:
          Name:
            NameFull: Bolleddula J
      – PersonEntity:
          Name:
            NameFull: Boulu L
      – PersonEntity:
          Name:
            NameFull: Fu Q
      – PersonEntity:
          Name:
            NameFull: Kotsuma M
      – PersonEntity:
          Name:
            NameFull: Leblanc AF
      – PersonEntity:
          Name:
            NameFull: Lewis G
      – PersonEntity:
          Name:
            NameFull: Liang G
      – PersonEntity:
          Name:
            NameFull: Parrott N
      – PersonEntity:
          Name:
            NameFull: Pilla Reddy V
      – PersonEntity:
          Name:
            NameFull: Prakash C
      – PersonEntity:
          Name:
            NameFull: Shah K
      – PersonEntity:
          Name:
            NameFull: Umehara K
      – PersonEntity:
          Name:
            NameFull: Mukherjee D
      – PersonEntity:
          Name:
            NameFull: Rehmel J
      – PersonEntity:
          Name:
            NameFull: Hariparsad N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2025 Feb
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1532-6535
          Numbering:
            – Type: volume
              Value: 117
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Clinical pharmacology and therapeutics
              Type: main
ResultId 1