Single-cell transcriptomics of pediatric Burkitt lymphoma reveals intra-tumor heterogeneity and markers of therapy resistance.

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Title: Single-cell transcriptomics of pediatric Burkitt lymphoma reveals intra-tumor heterogeneity and markers of therapy resistance.
Authors: Corinaldesi C; Institute for Cancer Genetics, Columbia University, New York, NY, USA., Holmes AB; Institute for Cancer Genetics, Columbia University, New York, NY, USA., Martire G; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Tosato A; Institute for Cancer Genetics, Columbia University, New York, NY, USA.; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Rizzato D; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy., Lovisa F; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Gallingani I; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Shen Q; Institute for Cancer Genetics, Columbia University, New York, NY, USA., Ferrone L; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy., Harris M; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Davies K; Dana-Farber Cancer Institute, Boston, MA, USA., Molinaro L; Department of Medical Science, University of Torino, Torino, Italy., Mortara U; Department of Medical Science, University of Torino, Torino, Italy., Dei Tos AP; General Pathology and Cytopathology Unit, Department of Medicine-DMED, University-Hospital of Padova, Padova, Italy., Ofori K; Department of Pathology & Cell Biology, Columbia University, New York, NY, USA., D'Amore ESG; Department of Pathology, San Bortolo Hospital, Vicenza, Italy., Chiarle R; Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.; European Institute of Oncology IRCCS, Division of Hematopathology, Milan, Italy., Ngan B; Hospital for Sick Children (SickKids), Toronto, ON, Canada., Carraro E; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy., Pillon M; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy., Hussein S; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bhagat G; Department of Pathology & Cell Biology, Columbia University, New York, NY, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA., Pizzi M; General Pathology and Cytopathology Unit, Department of Medicine-DMED, University-Hospital of Padova, Padova, Italy., Mussolin L; Maternal and Child Health Department, University-Hospital of Padova, Padova, Italy. lara.mussolin@unipd.it.; Istituto di Ricerca Pediatrica Citta' della Speranza, Padova, Italy. lara.mussolin@unipd.it., Basso K; Institute for Cancer Genetics, Columbia University, New York, NY, USA. kb451@cumc.columbia.edu.; Department of Pathology & Cell Biology, Columbia University, New York, NY, USA. kb451@cumc.columbia.edu.
Source: Leukemia [Leukemia] 2025 Jan; Vol. 39 (1), pp. 189-198. Date of Electronic Publication: 2024 Oct 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5551
DOI:10.1038/s41375-024-02431-3