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Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.

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Title: Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.
Authors: Lee WP; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Choi SH; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Shea MG; Biostatistics and Epidemiology Data Analytics Center, Boston University School of Public Health, Boston, Massachusetts, USA., Cheng PL; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Dombroski BA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Pitsillides AN; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Heard-Costa NL; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Framingham Heart Study, Framingham, Massachusetts, USA., Wang H; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Bulekova K; Research Computing Services, Information Services & Technology, Boston University, Boston, Massachusetts, USA., Kuzma AB; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Leung YY; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Farrell JJ; Biomedical Genetics, Department of Medicine, Boston University Medical School, Boston, Massachusetts, USA., Lin H; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA., Kunkle BW; John P. Hussman Institute for Human Genomics, Miami, Florida, USA.; John T. Macdonald Department of Human Genetics, Miami, Florida, USA., Naj A; Department of Biostatistics, Epidemiology, and Informatics, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Blue EE; Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, Washington, USA.; Brotman Baty Institute for Precision Medicine, Seattle, Washington, USA., Nusetor F; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Wang D; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Boerwinkle E; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA., Bush WS; Cleveland Institute for Computational Biology, Cleveland, Ohio, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA., Zhang X; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Biomedical Genetics, Department of Medicine, Boston University Medical School, Boston, Massachusetts, USA., De Jager PL; Center for Translational and Computational Neuroimmunology, Columbia University Medical Center, New York, New York, USA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, Quebec, Canada., Farrer LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Framingham Heart Study, Framingham, Massachusetts, USA.; Biomedical Genetics, Department of Medicine, Boston University Medical School, Boston, Massachusetts, USA.; Department of Ophthalmology, Department of Medicine, Boston University Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA., Martin E; John P. Hussman Institute for Human Genomics, Miami, Florida, USA.; John T. Macdonald Department of Human Genetics, Miami, Florida, USA.; University of Miami Miller School of Medicine, Miami, Florida, USA., Pericak-Vance M; John P. Hussman Institute for Human Genomics, Miami, Florida, USA.; John T. Macdonald Department of Human Genetics, Miami, Florida, USA.; University of Miami Miller School of Medicine, Miami, Florida, USA., Seshadri S; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, Texas, USA., Wijsman EM; Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, Washington, USA.; Department of Biostatistics, University of Washington, Seattle, Washington, USA.; Department of Genome Sciences, University of Washington, Seattle, Washington, USA., Wang LS; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Schellenberg GD; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Destefano AL; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Haines JL; Cleveland Institute for Computational Biology, Cleveland, Ohio, USA.; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
Corporate Authors: Alzheimer's Disease Sequencing Project
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Dec; Vol. 20 (12), pp. 8470-8483. Date of Electronic Publication: 2024 Oct 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project.
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