The antipsychotic chlorpromazine reduces neuroinflammation by inhibiting microglial voltage-gated potassium channels.

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Title: The antipsychotic chlorpromazine reduces neuroinflammation by inhibiting microglial voltage-gated potassium channels.
Authors: Lee HY; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea., Lee Y; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea., Chung C; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea., Park SI; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.; Department of Physiology, Kangwon National University School of Medicine, Chuncheon, Republic of Korea., Shin HJ; Department of Anatomy, Brain Research Institute, Chungnam National University School of Medicine, Daejeon, Republic of Korea., Joe EH; Department of Pharmacology, Ajou University School of Medicine, Suwon, Republic of Korea., Lee SJ; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea., Kim DW; Department of Anatomy, Brain Research Institute, Chungnam National University School of Medicine, Daejeon, Republic of Korea.; Department of Oral Anatomy & Developmental Biology, Kyung Hee University College of Dentistry, Seoul, Republic of Korea., Jo SH; Department of Physiology, Kangwon National University School of Medicine, Chuncheon, Republic of Korea., Choi SY; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.
Source: Glia [Glia] 2025 Jan; Vol. 73 (1), pp. 210-227. Date of Electronic Publication: 2024 Oct 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8806785 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1136 (Electronic) Linking ISSN: 08941491 NLM ISO Abbreviation: Glia Subsets: MEDLINE
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  Data: The antipsychotic chlorpromazine reduces neuroinflammation by inhibiting microglial voltage-gated potassium channels.
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  Data: <searchLink fieldCode="AU" term="%22Lee+HY%22">Lee HY</searchLink>; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+Y%22">Lee Y</searchLink>; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chung+C%22">Chung C</searchLink>; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+SI%22">Park SI</searchLink>; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.; Department of Physiology, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Shin+HJ%22">Shin HJ</searchLink>; Department of Anatomy, Brain Research Institute, Chungnam National University School of Medicine, Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Joe+EH%22">Joe EH</searchLink>; Department of Pharmacology, Ajou University School of Medicine, Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SJ%22">Lee SJ</searchLink>; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DW%22">Kim DW</searchLink>; Department of Anatomy, Brain Research Institute, Chungnam National University School of Medicine, Daejeon, Republic of Korea.; Department of Oral Anatomy & Developmental Biology, Kyung Hee University College of Dentistry, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jo+SH%22">Jo SH</searchLink>; Department of Physiology, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+SY%22">Choi SY</searchLink>; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%228806785%22">Glia</searchLink> [Glia] 2025 Jan; Vol. 73 (1), pp. 210-227. <i>Date of Electronic Publication: </i>2024 Oct 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8806785 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-1136 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208941491%22">08941491 </searchLink><i>NLM ISO Abbreviation: </i>Glia <i>Subsets: </i>MEDLINE
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        Value: 10.1002/glia.24629
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        Text: English
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      – TitleFull: The antipsychotic chlorpromazine reduces neuroinflammation by inhibiting microglial voltage-gated potassium channels.
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              Text: 2025 Jan
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