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A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease.

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Title: A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease.
Authors: Thomas T; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.; Centre for Human Genetics, University of Oxford, Oxford, UK.; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK., Friedrich M; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK., Rich-Griffin C; Centre for Human Genetics, University of Oxford, Oxford, UK., Pohin M; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Agarwal D; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Pakpoor J; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.; Centre for Human Genetics, University of Oxford, Oxford, UK.; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK., Lee C; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Tandon R; University College London Hospitals NHS Foundation Trust, London, UK., Rendek A; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Aschenbrenner D; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK., Jainarayanan A; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Voda A; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Siu JHY; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Sanches-Peres R; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Nee E; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Sathananthan D; University of Adelaide, Adelaide, Australia.; Lyell McEwin Hospital, Adelaide, Australia., Kotliar D; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Todd P; Centre for Human Genetics, University of Oxford, Oxford, UK., Kiourlappou M; Centre for Human Genetics, University of Oxford, Oxford, UK., Gartner L; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK., Ilott N; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Issa F; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Hester J; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Turner J; Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK., Nayar S; Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre and NIHR Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Birmingham Tissue Analytics, Institute of Translational Medicine, University of Birmingham, Birmingham, UK., Mackerodt J; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Center for Health AI, University of Colorado Anschutz, Anschutz, CO, USA., Jonsson A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Brenner M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Raychaudhuri S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Kulicke R; Celsius Therapeutics, Cambridge, MA, USA., Ramsdell D; Celsius Therapeutics, Cambridge, MA, USA., Stransky N; Celsius Therapeutics, Cambridge, MA, USA., Pagliarini R; Celsius Therapeutics, Cambridge, MA, USA., Bielecki P; Celsius Therapeutics, Cambridge, MA, USA., Spies N; Celsius Therapeutics, Cambridge, MA, USA., Marsden B; Centre for Human Genetics, University of Oxford, Oxford, UK., Taylor S; Centre for Human Genetics, University of Oxford, Oxford, UK., Wagner A; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA.; The Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA., Klenerman P; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK., Walsh A; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK., Coles M; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Jostins-Dean L; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Powrie FM; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., Filer A; Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.; National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre and NIHR Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.; Birmingham Tissue Analytics, Institute of Translational Medicine, University of Birmingham, Birmingham, UK., Travis S; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK. simon.travis@kennedy.ox.ac.uk.; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK. simon.travis@kennedy.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. simon.travis@kennedy.ox.ac.uk., Uhlig HH; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK. holm.uhlig@ndm.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. holm.uhlig@ndm.ox.ac.uk.; Department of Paediatrics, University of Oxford, Oxford, UK. holm.uhlig@ndm.ox.ac.uk., Dendrou CA; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK. calliope.dendrou@kennedy.ox.ac.uk.; Centre for Human Genetics, University of Oxford, Oxford, UK. calliope.dendrou@kennedy.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. calliope.dendrou@kennedy.ox.ac.uk., Buckley CD; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK. christopher.buckley@kennedy.ox.ac.uk.; Translational Gastroenterology & Liver Unit, John Radcliffe Hospital, Headington, Oxford, UK. christopher.buckley@kennedy.ox.ac.uk.; Rheumatology Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK. christopher.buckley@kennedy.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. christopher.buckley@kennedy.ox.ac.uk.
Source: Nature immunology [Nat Immunol] 2024 Nov; Vol. 25 (11), pp. 2152-2165. Date of Electronic Publication: 2024 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
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