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An autonomous implantable device for the prevention of death from opioid overdose.

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Title: An autonomous implantable device for the prevention of death from opioid overdose.
Authors: Ciatti JL; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA., Vázquez-Guardado A; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.; Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC 27606, USA., Brings VE; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Park J; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA., Ruyle B; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Neuroscience, Washington University, St. Louis, MO 63110, USA., Ober RA; Center for Comparative Medicine, Northwestern University, Evanston, IL 60208, USA.; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., McLuckie AJ; Center for Comparative Medicine, Northwestern University, Evanston, IL 60208, USA., Talcott MR; Division of Cardiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Carter EA; Center for Comparative Medicine, Northwestern University, Evanston, IL 60208, USA., Burrell AR; Center for Comparative Medicine, Northwestern University, Evanston, IL 60208, USA., Sponenburg RA; Chemistry of Life Processes Institute (Quantitative Bio-element Imaging Center), Northwestern University, Evanston, IL 60208, USA., Trueb J; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA., Gupta P; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Kim J; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA., Avila R; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA., Seong M; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA., Slivicki RA; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Kaplan MA; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA., Villalpando-Hernandez B; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA., Massaly N; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Montana MC; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA., Pet M; Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Huang Y; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.; Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA., Morón JA; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Neuroscience, Washington University, St. Louis, MO 63110, USA., Gereau RW 4th; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Neuroscience, Washington University, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, Washington University, St. Louis, MO 63110, USA., Rogers JA; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Source: Science advances [Sci Adv] 2024 Oct 25; Vol. 10 (43), pp. eadr3567. Date of Electronic Publication: 2024 Oct 23.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Ciatti+JL%22">Ciatti JL</searchLink>; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Vázquez-Guardado+A%22">Vázquez-Guardado A</searchLink>; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.; Department of Electrical and Computer Engineering, North Carolina State University, Raleigh, NC 27606, USA.<br /><searchLink fieldCode="AU" term="%22Brings+VE%22">Brings VE</searchLink>; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Ruyle+B%22">Ruyle B</searchLink>; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Neuroscience, Washington University, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Ober+RA%22">Ober RA</searchLink>; Center for Comparative Medicine, Northwestern University, Evanston, IL 60208, USA.; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22McLuckie+AJ%22">McLuckie AJ</searchLink>; Center for Comparative Medicine, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Talcott+MR%22">Talcott MR</searchLink>; Division of Cardiology, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Carter+EA%22">Carter EA</searchLink>; Center for Comparative Medicine, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Burrell+AR%22">Burrell AR</searchLink>; 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Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Slivicki+RA%22">Slivicki RA</searchLink>; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Kaplan+MA%22">Kaplan MA</searchLink>; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Villalpando-Hernandez+B%22">Villalpando-Hernandez B</searchLink>; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Massaly+N%22">Massaly N</searchLink>; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Montana+MC%22">Montana MC</searchLink>; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Pet+M%22">Pet M</searchLink>; Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Department of Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.; Department of Civil and Environmental Engineering, Northwestern University, Evanston, IL 60208, USA.<br /><searchLink fieldCode="AU" term="%22Morón+JA%22">Morón JA</searchLink>; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Neuroscience, Washington University, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Gereau+RW+4th%22">Gereau RW 4th</searchLink>; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Neuroscience, Washington University, St. Louis, MO 63110, USA.; Department of Biomedical Engineering, Washington University, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Rogers+JA%22">Rogers JA</searchLink>; Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, IL 60208, USA.; Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.; Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
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