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PCNA-binding activity separates RNF168 functions in DNA replication and DNA double-stranded break signaling.

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Title: PCNA-binding activity separates RNF168 functions in DNA replication and DNA double-stranded break signaling.
Authors: Yang Y; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA., Jayaprakash D; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.; Oral and Craniofacial Biomedicine Program, Adam's School of Dentistry, University of North Carolina at Chapel Hill, 385 S Columbia Street, Chapel Hill, NC 27599, USA., Jhujh SS; Institute of Cancer and Genomic Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK., Reynolds JJ; Institute of Cancer and Genomic Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK., Chen S; Cytiva Life Sciences, Global Life Sciences Solutions USA LLC, 100 Results Way, Marlborough, MA 01752, USA., Gao Y; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA., Anand JR; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA., Mutter-Rottmayer E; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA., Ariel P; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA., An J; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.; Institute of Cancer Prevention and Treatment, Harbin Medical University, 6 Bao Jian Street, Nan Gang District, Harbin 150081, China., Cheng X; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.; Department of Neuro-Oncology, Chongqing University Cancer Hospital and Chongqing Cancer Institute and Chongqing Cancer Hospital,181 Hanyu Road, Shapingba District, Chongqing 400044, China., Pearce KH; Center For Integrated Chemical Biology and Drug Discovery, UNC Eshelman School of Pharmacy, Marsico Hall, 125 Mason Farm Road, CB# 7363, Chapel Hill, NC 27599, USA., Blanchet SA; CHU de Québec-Université Laval Research Center (Oncology division), Université Laval Cancer Research Center and Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medecine, Université Laval, 9 McMahon, Québec, Canada., Nandakumar N; CHU de Québec-Université Laval Research Center (Oncology division), Université Laval Cancer Research Center and Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medecine, Université Laval, 9 McMahon, Québec, Canada., Zhou P; Department of Biochemistry, Duke University School of Medicine, 307 Research Drive, Durham, NC 27710, USA., Fradet-Turcotte A; CHU de Québec-Université Laval Research Center (Oncology division), Université Laval Cancer Research Center and Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medecine, Université Laval, 9 McMahon, Québec, Canada., Stewart GS; Institute of Cancer and Genomic Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK., Vaziri C; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.
Source: Nucleic acids research [Nucleic Acids Res] 2024 Nov 27; Vol. 52 (21), pp. 13019-13035.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PCNA-binding activity separates RNF168 functions in DNA replication and DNA double-stranded break signaling.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Jayaprakash+D%22">Jayaprakash D</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.; Oral and Craniofacial Biomedicine Program, Adam's School of Dentistry, University of North Carolina at Chapel Hill, 385 S Columbia Street, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Jhujh+SS%22">Jhujh SS</searchLink>; Institute of Cancer and Genomic Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK.<br /><searchLink fieldCode="AU" term="%22Reynolds+JJ%22">Reynolds JJ</searchLink>; Institute of Cancer and Genomic Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Cytiva Life Sciences, Global Life Sciences Solutions USA LLC, 100 Results Way, Marlborough, MA 01752, USA.<br /><searchLink fieldCode="AU" term="%22Gao+Y%22">Gao Y</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Anand+JR%22">Anand JR</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Mutter-Rottmayer+E%22">Mutter-Rottmayer E</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Ariel+P%22">Ariel P</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22An+J%22">An J</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.; Institute of Cancer Prevention and Treatment, Harbin Medical University, 6 Bao Jian Street, Nan Gang District, Harbin 150081, China.<br /><searchLink fieldCode="AU" term="%22Cheng+X%22">Cheng X</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.; Department of Neuro-Oncology, Chongqing University Cancer Hospital and Chongqing Cancer Institute and Chongqing Cancer Hospital,181 Hanyu Road, Shapingba District, Chongqing 400044, China.<br /><searchLink fieldCode="AU" term="%22Pearce+KH%22">Pearce KH</searchLink>; Center For Integrated Chemical Biology and Drug Discovery, UNC Eshelman School of Pharmacy, Marsico Hall, 125 Mason Farm Road, CB# 7363, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Blanchet+SA%22">Blanchet SA</searchLink>; CHU de Québec-Université Laval Research Center (Oncology division), Université Laval Cancer Research Center and Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medecine, Université Laval, 9 McMahon, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Nandakumar+N%22">Nandakumar N</searchLink>; CHU de Québec-Université Laval Research Center (Oncology division), Université Laval Cancer Research Center and Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medecine, Université Laval, 9 McMahon, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Zhou+P%22">Zhou P</searchLink>; Department of Biochemistry, Duke University School of Medicine, 307 Research Drive, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Fradet-Turcotte+A%22">Fradet-Turcotte A</searchLink>; CHU de Québec-Université Laval Research Center (Oncology division), Université Laval Cancer Research Center and Department of Molecular Biology, Medical Biochemistry and Pathology, Faculty of Medecine, Université Laval, 9 McMahon, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Stewart+GS%22">Stewart GS</searchLink>; Institute of Cancer and Genomic Sciences, University of Birmingham, Vincent Drive, Edgbaston, Birmingham B15 2TT, UK.<br /><searchLink fieldCode="AU" term="%22Vaziri+C%22">Vaziri C</searchLink>; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.
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