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Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles.

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Title: Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles.
Authors: Darguzyte M; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Antczak P; Department II of Internal Medicine, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Cologne Cluster of Excellence on Cellular Stress Responses in Ageing-Associated Diseases, 50931 Cologne, Germany., Bachurski D; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Mildred Scheel School of Oncology Aachen Bonn Cologne Düsseldorf, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany., Hoelker P; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Abedpour N; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of Translational Genomics, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Gholamipoorfard R; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of Translational Genomics, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Schlößer HA; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Wennhold K; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Thelen M; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Garcia-Marquez MA; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Koenig J; Department of Hematology, Oncology, Hemostasis and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany., Schneider A; Department of Hematology, Oncology, Hemostasis and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany., Braun T; Department of Hematology, Oncology, Hemostasis and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany., Klawonn F; Department of Computer Science, Ostfalia University of Applied Sciences, 38302 Wolfenbuettel, Germany.; Biostatistics Group, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany., Damrat M; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Rahman M; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Kleid JM; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., Theobald SJ; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Division of Infectious Diseases, Department I of Internal Medicine, University Hospital of Cologne, 50931 Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany., Bauer E; Institute of Transfusion Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany., von Kaisenberg C; Department of Obstetrics, Gynecology and Reproductive Medicine, Hannover Medical School, 30625 Hannover, Germany., Talbot SR; Institute for Laboratory Animal Science, Hannover Medical School, 30625 Hannover, Germany., Shultz LD; The Jackson Laboratory, Bar Harbor, ME 04609, USA., Soper B; The Jackson Laboratory, Bar Harbor, ME 04609, USA., Stripecke R; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department II of Internal Medicine, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of Hematology, Oncology, Hemostasis and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
Source: Cells [Cells] 2024 Oct 12; Vol. 13 (20). Date of Electronic Publication: 2024 Oct 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Long-Term Human Immune Reconstitution, T-Cell Development, and Immune Reactivity in Mice Lacking the Murine Major Histocompatibility Complex: Validation with Cellular and Gene Expression Profiles.
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  Data: <searchLink fieldCode="AU" term="%22Darguzyte+M%22">Darguzyte M</searchLink>; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Antczak+P%22">Antczak P</searchLink>; Department II of Internal Medicine, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Cologne Cluster of Excellence on Cellular Stress Responses in Ageing-Associated Diseases, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Bachurski+D%22">Bachurski D</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Mildred Scheel School of Oncology Aachen Bonn Cologne Düsseldorf, Faculty of Medicine and University Hospital of Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Hoelker+P%22">Hoelker P</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Abedpour+N%22">Abedpour N</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of Translational Genomics, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Gholamipoorfard+R%22">Gholamipoorfard R</searchLink>; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of Translational Genomics, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Schlößer+HA%22">Schlößer HA</searchLink>; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Wennhold+K%22">Wennhold K</searchLink>; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Thelen+M%22">Thelen M</searchLink>; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Garcia-Marquez+MA%22">Garcia-Marquez MA</searchLink>; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of General, Visceral, Cancer and Transplantation Surgery, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Koenig+J%22">Koenig J</searchLink>; 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Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Rahman+M%22">Rahman M</searchLink>; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Kleid+JM%22">Kleid JM</searchLink>; Institute for Translational Immune-Oncology, Cancer Research Center Cologne-Essen (CCCE), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; 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Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department II of Internal Medicine, Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and University Hospital Cologne, University of Cologne, 50931 Cologne, Germany.; Department of Hematology, Oncology, Hemostasis and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, 50931 Cologne, Germany.
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