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The D75N and P161S Mutations in the C0-C2 Fragment of cMyBP-C Associated with Hypertrophic Cardiomyopathy Disturb the Thin Filament Activation, Nucleotide Exchange in Myosin, and Actin-Myosin Interaction.

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Title: The D75N and P161S Mutations in the C0-C2 Fragment of cMyBP-C Associated with Hypertrophic Cardiomyopathy Disturb the Thin Filament Activation, Nucleotide Exchange in Myosin, and Actin-Myosin Interaction.
Authors: Kochurova AM; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia., Beldiia EA; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia., Nefedova VV; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia., Yampolskaya DS; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia., Koubassova NA; Institute of Mechanics, Moscow State University, 119192 Moscow, Russia., Kleymenov SY; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.; Koltzov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia., Antonets JY; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia., Ryabkova NS; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.; HyTest Ltd., 20520 Turku, Finland., Katrukha IA; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.; HyTest Ltd., 20520 Turku, Finland., Bershitsky SY; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia., Matyushenko AM; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia., Kopylova GV; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia., Shchepkin DV; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia.
Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 18; Vol. 25 (20). Date of Electronic Publication: 2024 Oct 18.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The D75N and P161S Mutations in the C0-C2 Fragment of cMyBP-C Associated with Hypertrophic Cardiomyopathy Disturb the Thin Filament Activation, Nucleotide Exchange in Myosin, and Actin-Myosin Interaction.
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  Data: <searchLink fieldCode="AU" term="%22Kochurova+AM%22">Kochurova AM</searchLink>; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia.<br /><searchLink fieldCode="AU" term="%22Beldiia+EA%22">Beldiia EA</searchLink>; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia.<br /><searchLink fieldCode="AU" term="%22Nefedova+VV%22">Nefedova VV</searchLink>; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Yampolskaya+DS%22">Yampolskaya DS</searchLink>; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Koubassova+NA%22">Koubassova NA</searchLink>; Institute of Mechanics, Moscow State University, 119192 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Kleymenov+SY%22">Kleymenov SY</searchLink>; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.; Koltzov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Antonets+JY%22">Antonets JY</searchLink>; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia.<br /><searchLink fieldCode="AU" term="%22Ryabkova+NS%22">Ryabkova NS</searchLink>; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.; HyTest Ltd., 20520 Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Katrukha+IA%22">Katrukha IA</searchLink>; Department of Biochemistry, Faculty of Biology, Lomonosov Moscow State University, 119991 Moscow, Russia.; HyTest Ltd., 20520 Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Bershitsky+SY%22">Bershitsky SY</searchLink>; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia.<br /><searchLink fieldCode="AU" term="%22Matyushenko+AM%22">Matyushenko AM</searchLink>; Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Kopylova+GV%22">Kopylova GV</searchLink>; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia.<br /><searchLink fieldCode="AU" term="%22Shchepkin+DV%22">Shchepkin DV</searchLink>; Institute of Immunology and Physiology of the Russian Academy of Sciences, 620049 Yekaterinburg, Russia.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2024 Oct 18; Vol. 25 (20). <i>Date of Electronic Publication: </i>2024 Oct 18.
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