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Novel metabolomic predictors of incident colorectal cancer in men and women.

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Title: Novel metabolomic predictors of incident colorectal cancer in men and women.
Authors: Downie JM; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Joshi AD; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Geraghty CM; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Guercio BJ; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Zeleznik OA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States., Song M; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Bever AM; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Drew DA; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States., Tabung FK; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Internal Medicine, Division of Medical Oncology, The Ohio State University College of Medicine and Comprehensive Cancer Center, Columbus, OH, United States., Zhang X; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Yale School of Nursing, Orange, CT, United States., Jin L; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States., Eliassen AH; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Willett WC; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Wu K; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Kraft P; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Tamimi R; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States., Clish C; Broad Institute of MIT and Harvard, Cambridge, MA, United States., Fuchs CS; Yale Cancer Center, New Haven, CT, United States.; Genentech and Roche, South San Francisco, CA, United States., Giovannucci E; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States., Meyerhardt JA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States., Chan AT; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.
Source: Journal of the National Cancer Institute [J Natl Cancer Inst] 2025 Mar 01; Vol. 117 (3), pp. 517-528.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print Cited Medium: Internet ISSN: 1460-2105 (Electronic) Linking ISSN: 00278874 NLM ISO Abbreviation: J Natl Cancer Inst Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Downie+JM%22">Downie JM</searchLink>; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Joshi+AD%22">Joshi AD</searchLink>; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Geraghty+CM%22">Geraghty CM</searchLink>; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Guercio+BJ%22">Guercio BJ</searchLink>; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Zeleznik+OA%22">Zeleznik OA</searchLink>; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Song+M%22">Song M</searchLink>; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Bever+AM%22">Bever AM</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Drew+DA%22">Drew DA</searchLink>; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Tabung+FK%22">Tabung FK</searchLink>; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Internal Medicine, Division of Medical Oncology, The Ohio State University College of Medicine and Comprehensive Cancer Center, Columbus, OH, United States.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Yale School of Nursing, Orange, CT, United States.<br /><searchLink fieldCode="AU" term="%22Jin+L%22">Jin L</searchLink>; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Eliassen+AH%22">Eliassen AH</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Willett+WC%22">Willett WC</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Wu+K%22">Wu K</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Kraft+P%22">Kraft P</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Tamimi+R%22">Tamimi R</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Clish+C%22">Clish C</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, United States.<br /><searchLink fieldCode="AU" term="%22Fuchs+CS%22">Fuchs CS</searchLink>; Yale Cancer Center, New Haven, CT, United States.; Genentech and Roche, South San Francisco, CA, United States.<br /><searchLink fieldCode="AU" term="%22Giovannucci+E%22">Giovannucci E</searchLink>; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Meyerhardt+JA%22">Meyerhardt JA</searchLink>; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, United States.<br /><searchLink fieldCode="AU" term="%22Chan+AT%22">Chan AT</searchLink>; Clinical and Translational Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States.
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