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Shortcomings, limitations and gaps in physiological roles of extracellular vesicles in obesity.

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Title: Shortcomings, limitations and gaps in physiological roles of extracellular vesicles in obesity.
Authors: Valero P; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Health Sciences, Universidad de Talca, Talca, Chile., Silva K; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Institute of Chemistry, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile., Valenzuela-Hinrichsen A; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Vásquez A; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Espinoza F; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile., Lira F; Faculty of Medicine, Universidad de Antofagasta, Antofagasta, Chile., Cornejo M; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Health Sciences, Universidad de Talca, Talca, Chile.; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.; Biomedical Department, Faculty of Health Sciences, Universidad de Antofagasta, Antofagasta, Chile., Fuentes G; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Health Sciences, Universidad de Talca, Talca, Chile.; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands., González D; Faculty of Health Sciences, Universidad de Talca, Talca, Chile., Moore-Carrasco R; Faculty of Health Sciences, Universidad de Talca, Talca, Chile., van der Beek EM; Department of Pediatrics, University of Groningen, University Medical Center Groningen (UMCG), Groningen, The Netherlands.; Nestlé Institute for Health Sciences, Nestlé Research, Societé des Produits de Nestlé, Lausanne, Switzerland., Hillebrands JL; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands., van Goor H; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands., Grismaldo A; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Excellence program, School of Medicine and Health Sciences, The Institute for Obesity Research (IOR), Eutra, Tecnologico de Monterrey, Monterrey, Nuevo León, Mexico., Sobrevia L; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.; Faculty of Excellence program, School of Medicine and Health Sciences, The Institute for Obesity Research (IOR), Eutra, Tecnologico de Monterrey, Monterrey, Nuevo León, Mexico.; Department of Physiology, Faculty of Pharmacy, Universidad de Sevilla, Seville, Spain.; Medical School (Faculty of Medicine), Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.; University of Queensland Centre for Clinical Research (UQCCR), Faculty of Medicine and Biomedical Sciences, University of Queensland, Herston, Queensland, Australia.
Source: The Journal of physiology [J Physiol] 2026 Jun; Vol. 604 (11), pp. 4092-4114. Date of Electronic Publication: 2024 Oct 29.
Publication Type: Journal Article; Review
Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE
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  Data: Shortcomings, limitations and gaps in physiological roles of extracellular vesicles in obesity.
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  Data: <searchLink fieldCode="AU" term="%22Valero+P%22">Valero P</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Health Sciences, Universidad de Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Silva+K%22">Silva K</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Institute of Chemistry, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.<br /><searchLink fieldCode="AU" term="%22Valenzuela-Hinrichsen+A%22">Valenzuela-Hinrichsen A</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Vásquez+A%22">Vásquez A</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Espinoza+F%22">Espinoza F</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Lira+F%22">Lira F</searchLink>; Faculty of Medicine, Universidad de Antofagasta, Antofagasta, Chile.<br /><searchLink fieldCode="AU" term="%22Cornejo+M%22">Cornejo M</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Health Sciences, Universidad de Talca, Talca, Chile.; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.; Biomedical Department, Faculty of Health Sciences, Universidad de Antofagasta, Antofagasta, Chile.<br /><searchLink fieldCode="AU" term="%22Fuentes+G%22">Fuentes G</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Health Sciences, Universidad de Talca, Talca, Chile.; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22González+D%22">González D</searchLink>; Faculty of Health Sciences, Universidad de Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22Moore-Carrasco+R%22">Moore-Carrasco R</searchLink>; Faculty of Health Sciences, Universidad de Talca, Talca, Chile.<br /><searchLink fieldCode="AU" term="%22van+der+Beek+EM%22">van der Beek EM</searchLink>; Department of Pediatrics, University of Groningen, University Medical Center Groningen (UMCG), Groningen, The Netherlands.; Nestlé Institute for Health Sciences, Nestlé Research, Societé des Produits de Nestlé, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hillebrands+JL%22">Hillebrands JL</searchLink>; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Goor+H%22">van Goor H</searchLink>; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Grismaldo+A%22">Grismaldo A</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Faculty of Excellence program, School of Medicine and Health Sciences, The Institute for Obesity Research (IOR), Eutra, Tecnologico de Monterrey, Monterrey, Nuevo León, Mexico.<br /><searchLink fieldCode="AU" term="%22Sobrevia+L%22">Sobrevia L</searchLink>; Cellular and Molecular Physiology Laboratory (CMPL), Department of Obstetrics, Division of Obstetrics and Gynaecology, School of Medicine, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.; Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Centre Groningen (UMCG), Groningen, The Netherlands.; Faculty of Excellence program, School of Medicine and Health Sciences, The Institute for Obesity Research (IOR), Eutra, Tecnologico de Monterrey, Monterrey, Nuevo León, Mexico.; Department of Physiology, Faculty of Pharmacy, Universidad de Sevilla, Seville, Spain.; Medical School (Faculty of Medicine), Sao Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.; University of Queensland Centre for Clinical Research (UQCCR), Faculty of Medicine and Biomedical Sciences, University of Queensland, Herston, Queensland, Australia.
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