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Comprehensive analysis of mesenchymal cells reveals a dysregulated TGF-β/WNT/HOXB7 axis in patients with myelofibrosis.

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Title: Comprehensive analysis of mesenchymal cells reveals a dysregulated TGF-β/WNT/HOXB7 axis in patients with myelofibrosis.
Authors: Ganesan S; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France., Awan-Toor S; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France., Guidez F; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; INSERM U1232/LNC, Team Epi2THM, Université Bourgogne Franche-Comté, Dijon, France., Maslah N; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France., Rahimy R; Laboratoire de recherche en génétique et hématologie translationnelle, Institut Gonçalo Moniz, Salvador, Bahia, Brazil., Aoun C; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France., Gou P; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France., Guiguen C; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France., Soret J; INSERM CIC 1427, Université Paris Cité, Centre d'Investigations Cliniques, Hôpital Saint-Louis, AP-HP, Paris, France., Ravdan O; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France., Bisio V; INSERM UMRS 1160, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France., Dulphy N; INSERM UMRS 1160, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France.; Laboratoire d'Immunologie et d'Histocompatibilite, Hôpital Saint-Louis, AP-HP, Paris, France., Lobry C; INSERM U944, CNRS UMR7212, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France., Schlageter MH; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France., Souyri M; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France., Giraudier S; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France., Kiladjian JJ; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; INSERM CIC 1427, Université Paris Cité, Centre d'Investigations Cliniques, Hôpital Saint-Louis, AP-HP, Paris, France., Chomienne C; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France., Cassinat B; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France.
Source: JCI insight [JCI Insight] 2024 Dec 06; Vol. 9 (23). Date of Electronic Publication: 2024 Dec 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: Comprehensive analysis of mesenchymal cells reveals a dysregulated TGF-β/WNT/HOXB7 axis in patients with myelofibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Ganesan+S%22">Ganesan S</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Awan-Toor+S%22">Awan-Toor S</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Guidez+F%22">Guidez F</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; INSERM U1232/LNC, Team Epi2THM, Université Bourgogne Franche-Comté, Dijon, France.<br /><searchLink fieldCode="AU" term="%22Maslah+N%22">Maslah N</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rahimy+R%22">Rahimy R</searchLink>; Laboratoire de recherche en génétique et hématologie translationnelle, Institut Gonçalo Moniz, Salvador, Bahia, Brazil.<br /><searchLink fieldCode="AU" term="%22Aoun+C%22">Aoun C</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gou+P%22">Gou P</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Guiguen+C%22">Guiguen C</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Soret+J%22">Soret J</searchLink>; INSERM CIC 1427, Université Paris Cité, Centre d'Investigations Cliniques, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ravdan+O%22">Ravdan O</searchLink>; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bisio+V%22">Bisio V</searchLink>; INSERM UMRS 1160, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dulphy+N%22">Dulphy N</searchLink>; INSERM UMRS 1160, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France.; Laboratoire d'Immunologie et d'Histocompatibilite, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Lobry+C%22">Lobry C</searchLink>; INSERM U944, CNRS UMR7212, Institut de Recherche Saint-Louis, Université Paris-Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Schlageter+MH%22">Schlageter MH</searchLink>; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Souyri+M%22">Souyri M</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Giraudier+S%22">Giraudier S</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Kiladjian+JJ%22">Kiladjian JJ</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; INSERM CIC 1427, Université Paris Cité, Centre d'Investigations Cliniques, Hôpital Saint-Louis, AP-HP, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chomienne+C%22">Chomienne C</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cassinat+B%22">Cassinat B</searchLink>; INSERM UMRS 1131, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France.; Service de Biologie Cellulaire, Hôpital Saint-Louis, AP-HP, Paris, France.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2024 Dec 06; Vol. 9 (23). <i>Date of Electronic Publication: </i>2024 Dec 06.
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