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Onvansertib in Combination With Chemotherapy and Bevacizumab in Second-Line Treatment of KRAS-Mutant Metastatic Colorectal Cancer: A Single-Arm, Phase II Trial.

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Title: Onvansertib in Combination With Chemotherapy and Bevacizumab in Second-Line Treatment of KRAS-Mutant Metastatic Colorectal Cancer: A Single-Arm, Phase II Trial.
Authors: Ahn DH; Division of Medical Oncology, Mayo Clinic, Phoenix, AZ., Ridinger M; Cardiff Oncology Inc, San Diego, CA., Cannon TL; Inova Schar Cancer Institute, Fairfax, VA., Mendelsohn L; Carti Cancer Center, Little Rock, AR., Starr JS; Division of Hematology and Oncology, Mayo Clinic, Jacksonville, FL., Hubbard JM; Division of Oncology, Department of Medicine, Mayo Clinic, Rochester, MN., Kasi A; Division of Medical Oncology, University of Kansas Medical Center, Kansas City, KS., Barzi A; Division of Medical Oncology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA., Samuëlsz E; Cardiff Oncology Inc, San Diego, CA., Karki A; Cardiff Oncology Inc, San Diego, CA., Subramanian RA; Cardiff Oncology Inc, San Diego, CA., Yemane D; Cardiff Oncology Inc, San Diego, CA., Kim R; Cardiff Oncology Inc, San Diego, CA., Wu CC; Cardiff Oncology Inc, San Diego, CA., Croucher PJP; Cardiff Oncology Inc, San Diego, CA., Smeal T; Cardiff Oncology Inc, San Diego, CA., Kabbinavar FF; Cardiff Oncology Inc, San Diego, CA., Lenz HJ; Division of Oncology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA.
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2025 Mar; Vol. 43 (7), pp. 840-851. Date of Electronic Publication: 2024 Oct 30.
Publication Type: Journal Article; Clinical Trial, Phase II; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Onvansertib in Combination With Chemotherapy and Bevacizumab in Second-Line Treatment of KRAS-Mutant Metastatic Colorectal Cancer: A Single-Arm, Phase II Trial.
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  Data: <searchLink fieldCode="AU" term="%22Ahn+DH%22">Ahn DH</searchLink>; Division of Medical Oncology, Mayo Clinic, Phoenix, AZ.<br /><searchLink fieldCode="AU" term="%22Ridinger+M%22">Ridinger M</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Cannon+TL%22">Cannon TL</searchLink>; Inova Schar Cancer Institute, Fairfax, VA.<br /><searchLink fieldCode="AU" term="%22Mendelsohn+L%22">Mendelsohn L</searchLink>; Carti Cancer Center, Little Rock, AR.<br /><searchLink fieldCode="AU" term="%22Starr+JS%22">Starr JS</searchLink>; Division of Hematology and Oncology, Mayo Clinic, Jacksonville, FL.<br /><searchLink fieldCode="AU" term="%22Hubbard+JM%22">Hubbard JM</searchLink>; Division of Oncology, Department of Medicine, Mayo Clinic, Rochester, MN.<br /><searchLink fieldCode="AU" term="%22Kasi+A%22">Kasi A</searchLink>; Division of Medical Oncology, University of Kansas Medical Center, Kansas City, KS.<br /><searchLink fieldCode="AU" term="%22Barzi+A%22">Barzi A</searchLink>; Division of Medical Oncology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Samuëlsz+E%22">Samuëlsz E</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Karki+A%22">Karki A</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Subramanian+RA%22">Subramanian RA</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Yemane+D%22">Yemane D</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Kim+R%22">Kim R</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Wu+CC%22">Wu CC</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Croucher+PJP%22">Croucher PJP</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Smeal+T%22">Smeal T</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Kabbinavar+FF%22">Kabbinavar FF</searchLink>; Cardiff Oncology Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Lenz+HJ%22">Lenz HJ</searchLink>; Division of Oncology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA.
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  Data: <searchLink fieldCode="JN" term="%228309333%22">Journal of clinical oncology : official journal of the American Society of Clinical Oncology</searchLink> [J Clin Oncol] 2025 Mar; Vol. 43 (7), pp. 840-851. <i>Date of Electronic Publication: </i>2024 Oct 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Clinical+Oncology%22">American Society of Clinical Oncology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8309333 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-7755 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220732183X%22">0732183X </searchLink><i>NLM ISO Abbreviation: </i>J Clin Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1200/JCO-24-01266
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        Text: English
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              Text: 2025 Mar
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