View in EDS

CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.

Saved in:
Bibliographic Details
Title: CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.
Authors: Jin Y; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA., Basu S; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA., Feng M; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA., Ning Y; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA., Munasinghe I; Synthetic Chemical Biology Core Laboratory, The University of Kansas, Lawrence, KS, 66047, USA., Joachim AM; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA., Li J; College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA., Qin L; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA., Madden R; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA., Burks H; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA., Gao P; Protein Production Group, The University of Kansas, Lawrence, KS, 66047, USA., Wu JQ; Department of Pharmacy Practice, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA., Sheikh SW; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA., Joice AC; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA., Perera C; Synthetic Chemical Biology Core Laboratory, The University of Kansas, Lawrence, KS, 66047, USA., Werbovetz KA; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA., Zhang K; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA., Wang MZ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA. michael.wang@ku.edu.
Source: Nature communications [Nat Commun] 2024 Oct 31; Vol. 15 (1), pp. 9409. Date of Electronic Publication: 2024 Oct 31.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39482311
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Jin+Y%22">Jin Y</searchLink>; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA.<br /><searchLink fieldCode="AU" term="%22Basu+S%22">Basu S</searchLink>; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA.<br /><searchLink fieldCode="AU" term="%22Feng+M%22">Feng M</searchLink>; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA.<br /><searchLink fieldCode="AU" term="%22Ning+Y%22">Ning Y</searchLink>; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA.<br /><searchLink fieldCode="AU" term="%22Munasinghe+I%22">Munasinghe I</searchLink>; Synthetic Chemical Biology Core Laboratory, The University of Kansas, Lawrence, KS, 66047, USA.<br /><searchLink fieldCode="AU" term="%22Joachim+AM%22">Joachim AM</searchLink>; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Qin+L%22">Qin L</searchLink>; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA.<br /><searchLink fieldCode="AU" term="%22Madden+R%22">Madden R</searchLink>; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA.<br /><searchLink fieldCode="AU" term="%22Burks+H%22">Burks H</searchLink>; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA.<br /><searchLink fieldCode="AU" term="%22Gao+P%22">Gao P</searchLink>; Protein Production Group, The University of Kansas, Lawrence, KS, 66047, USA.<br /><searchLink fieldCode="AU" term="%22Wu+JQ%22">Wu JQ</searchLink>; Department of Pharmacy Practice, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA.<br /><searchLink fieldCode="AU" term="%22Sheikh+SW%22">Sheikh SW</searchLink>; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA.<br /><searchLink fieldCode="AU" term="%22Joice+AC%22">Joice AC</searchLink>; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Perera+C%22">Perera C</searchLink>; Synthetic Chemical Biology Core Laboratory, The University of Kansas, Lawrence, KS, 66047, USA.<br /><searchLink fieldCode="AU" term="%22Werbovetz+KA%22">Werbovetz KA</searchLink>; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+K%22">Zhang K</searchLink>; Department of Biological Sciences, Texas Tech University, Lubbock, TX, 79409, USA.<br /><searchLink fieldCode="AU" term="%22Wang+MZ%22">Wang MZ</searchLink>; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS, 66047, USA. michael.wang@ku.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Oct 31; Vol. 15 (1), pp. 9409. <i>Date of Electronic Publication: </i>2024 Oct 31.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39482311
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-024-53790-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 9409
    Titles:
      – TitleFull: CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Jin Y
      – PersonEntity:
          Name:
            NameFull: Basu S
      – PersonEntity:
          Name:
            NameFull: Feng M
      – PersonEntity:
          Name:
            NameFull: Ning Y
      – PersonEntity:
          Name:
            NameFull: Munasinghe I
      – PersonEntity:
          Name:
            NameFull: Joachim AM
      – PersonEntity:
          Name:
            NameFull: Li J
      – PersonEntity:
          Name:
            NameFull: Qin L
      – PersonEntity:
          Name:
            NameFull: Madden R
      – PersonEntity:
          Name:
            NameFull: Burks H
      – PersonEntity:
          Name:
            NameFull: Gao P
      – PersonEntity:
          Name:
            NameFull: Wu JQ
      – PersonEntity:
          Name:
            NameFull: Sheikh SW
      – PersonEntity:
          Name:
            NameFull: Joice AC
      – PersonEntity:
          Name:
            NameFull: Perera C
      – PersonEntity:
          Name:
            NameFull: Werbovetz KA
      – PersonEntity:
          Name:
            NameFull: Zhang K
      – PersonEntity:
          Name:
            NameFull: Wang MZ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 31
              M: 10
              Text: 2024 Oct 31
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 15
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1