Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape.
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| Title: | Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape. |
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| Authors: | Muir DF; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Program in Biophysics, University of California, San Francisco, San Francisco, CA, USA., Asper GPR; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Notin P; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Computer Science, University of Oxford, Oxford, UK., Posner JA; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Department of Biology, San Francisco State University, San Francisco, CA, USA., Marks DS; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Keiser MJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA.; Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA., Pinney MM; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Valhalla Fellow, University of California San Francisco, San Francisco, CA, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39484523 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Muir+DF%22">Muir DF</searchLink>; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Program in Biophysics, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Asper+GPR%22">Asper GPR</searchLink>; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Notin+P%22">Notin P</searchLink>; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Computer Science, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Posner+JA%22">Posner JA</searchLink>; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Department of Biology, San Francisco State University, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Marks+DS%22">Marks DS</searchLink>; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Keiser+MJ%22">Keiser MJ</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA.; Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pinney+MM%22">Pinney MM</searchLink>; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Valhalla Fellow, University of California San Francisco, San Francisco, CA, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2024 Oct 25. <i>Date of Electronic Publication: </i>2024 Oct 25. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39484523 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1101/2024.10.23.619915 Languages: – Code: eng Text: English Titles: – TitleFull: Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Muir DF – PersonEntity: Name: NameFull: Asper GPR – PersonEntity: Name: NameFull: Notin P – PersonEntity: Name: NameFull: Posner JA – PersonEntity: Name: NameFull: Marks DS – PersonEntity: Name: NameFull: Keiser MJ – PersonEntity: Name: NameFull: Pinney MM IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 10 Text: 2024 Oct 25 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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