Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape.
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| Title: | Evolutionary-Scale Enzymology Enables Biochemical Constant Prediction Across a Multi-Peaked Catalytic Landscape. |
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| Authors: | Muir DF; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Program in Biophysics, University of California, San Francisco, San Francisco, CA, USA., Asper GPR; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA., Notin P; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Computer Science, University of Oxford, Oxford, UK., Posner JA; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Department of Biology, San Francisco State University, San Francisco, CA, USA., Marks DS; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Keiser MJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA.; Institute for Neurodegenerative Diseases, University of California, San Francisco, San Francisco, CA, USA.; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA., Pinney MM; Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA.; Valhalla Fellow, University of California San Francisco, San Francisco, CA, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 25. Date of Electronic Publication: 2024 Oct 25. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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