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Impaired suppression of fatty acid release by insulin is a strong predictor of reduced whole-body insulin-mediated glucose uptake and skeletal muscle insulin receptor activation.

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Title: Impaired suppression of fatty acid release by insulin is a strong predictor of reduced whole-body insulin-mediated glucose uptake and skeletal muscle insulin receptor activation.
Authors: Schleh MW; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Ryan BJ; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Ahn C; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Ludzki AC; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Van Pelt DW; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Pitchford LM; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Chugh OK; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Luker AT; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA., Luker KE; Center for Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA., Samovski D; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Abumrad NA; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA., Burant CF; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Horowitz JF; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.
Source: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2025 Jan; Vol. 241 (1), pp. e14249. Date of Electronic Publication: 2024 Nov 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262545 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-1716 (Electronic) Linking ISSN: 17481708 NLM ISO Abbreviation: Acta Physiol (Oxf) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impaired suppression of fatty acid release by insulin is a strong predictor of reduced whole-body insulin-mediated glucose uptake and skeletal muscle insulin receptor activation.
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  Data: <searchLink fieldCode="AU" term="%22Schleh+MW%22">Schleh MW</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Ryan+BJ%22">Ryan BJ</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Ahn+C%22">Ahn C</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Ludzki+AC%22">Ludzki AC</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Van+Pelt+DW%22">Van Pelt DW</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Pitchford+LM%22">Pitchford LM</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Chugh+OK%22">Chugh OK</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Luker+AT%22">Luker AT</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Luker+KE%22">Luker KE</searchLink>; Center for Molecular Imaging, Department of Radiology, University of Michigan, Ann Arbor, Michigan, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Samovski+D%22">Samovski D</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Abumrad+NA%22">Abumrad NA</searchLink>; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Burant+CF%22">Burant CF</searchLink>; Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Horowitz+JF%22">Horowitz JF</searchLink>; Substrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.
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  Data: <searchLink fieldCode="JN" term="%22101262545%22">Acta physiologica (Oxford, England)</searchLink> [Acta Physiol (Oxf)] 2025 Jan; Vol. 241 (1), pp. e14249. <i>Date of Electronic Publication: </i>2024 Nov 01.
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