Anti-integrin αvβ6 Autoantibodies Are Increased in Primary Sclerosing Cholangitis Patients With Concomitant Inflammatory Bowel Disease and Correlate With Liver Disease Severity.

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Title: Anti-integrin αvβ6 Autoantibodies Are Increased in Primary Sclerosing Cholangitis Patients With Concomitant Inflammatory Bowel Disease and Correlate With Liver Disease Severity.
Authors: Bloemen H; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Livanos AE; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: alexandra.livanos@mountsinai.org., Martins A; Schiff Center for Liver Diseases, University of Miami Leonard M. Miller School of Medicine, Miami, Florida., Dean R; Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, California., Bravo AC; Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal., Bourgonje AR; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Tankelevich M; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York., Herb J; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Cho J; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Santos AA; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal., Rodrigues CMP; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal., Petralia F; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York., Colombel JF; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Bowlus CL; Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, California., Schiano T; Recanati/Miller Transplantation Institute, Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York., Torres J; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal; Faculty of Medicine, Universidade de Lisboa, Lisbon, Portugal; Division of Gastroenterology, Hospital da Luz, Lisbon, Portugal., Levy C; Schiff Center for Liver Diseases, University of Miami Leonard M. Miller School of Medicine, Miami, Florida; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: clevy@med.miami.edu., Mehandru S; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: saurabh.mehandru@mssm.edu.
Source: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2025 Aug; Vol. 23 (9), pp. 1612-1622.e8. Date of Electronic Publication: 2024 Oct 25.
Publication Type: Journal Article
Journal Info: Publisher: W.B. Saunders for the American Gastroenterological Association Country of Publication: United States NLM ID: 101160775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-7714 (Electronic) Linking ISSN: 15423565 NLM ISO Abbreviation: Clin Gastroenterol Hepatol Subsets: MEDLINE
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  Data: Anti-integrin αvβ6 Autoantibodies Are Increased in Primary Sclerosing Cholangitis Patients With Concomitant Inflammatory Bowel Disease and Correlate With Liver Disease Severity.
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  Data: <searchLink fieldCode="AU" term="%22Bloemen+H%22">Bloemen H</searchLink>; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Livanos+AE%22">Livanos AE</searchLink>; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: alexandra.livanos@mountsinai.org.<br /><searchLink fieldCode="AU" term="%22Martins+A%22">Martins A</searchLink>; Schiff Center for Liver Diseases, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.<br /><searchLink fieldCode="AU" term="%22Dean+R%22">Dean R</searchLink>; Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, California.<br /><searchLink fieldCode="AU" term="%22Bravo+AC%22">Bravo AC</searchLink>; Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal.<br /><searchLink fieldCode="AU" term="%22Bourgonje+AR%22">Bourgonje AR</searchLink>; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Tankelevich+M%22">Tankelevich M</searchLink>; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Herb+J%22">Herb J</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Cho+J%22">Cho J</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Santos+AA%22">Santos AA</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Rodrigues+CMP%22">Rodrigues CMP</searchLink>; Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Petralia+F%22">Petralia F</searchLink>; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Colombel+JF%22">Colombel JF</searchLink>; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Bowlus+CL%22">Bowlus CL</searchLink>; Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, California.<br /><searchLink fieldCode="AU" term="%22Schiano+T%22">Schiano T</searchLink>; Recanati/Miller Transplantation Institute, Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.<br /><searchLink fieldCode="AU" term="%22Torres+J%22">Torres J</searchLink>; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Hospital Beatriz Ângelo, Loures, Portugal; Faculty of Medicine, Universidade de Lisboa, Lisbon, Portugal; Division of Gastroenterology, Hospital da Luz, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Levy+C%22">Levy C</searchLink>; Schiff Center for Liver Diseases, University of Miami Leonard M. Miller School of Medicine, Miami, Florida; Division of Digestive Health and Liver Diseases, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: clevy@med.miami.edu.<br /><searchLink fieldCode="AU" term="%22Mehandru+S%22">Mehandru S</searchLink>; Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: saurabh.mehandru@mssm.edu.
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