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Proximal and Classic Epithelioid Sarcomas are Distinct Molecular Entities Defined by MYC/GATA3 and SOX17/Endothelial Markers, Respectively.

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Title: Proximal and Classic Epithelioid Sarcomas are Distinct Molecular Entities Defined by MYC/GATA3 and SOX17/Endothelial Markers, Respectively.
Authors: Sigalotti L; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Frezza AM; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Sbaraglia M; Surgical Pathology and Cytopathology Unit, Department of Medicine-DIMED, University of Padua School of Medicine, Padua, Italy., Del Savio E; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Baldazzi D; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Valenti B; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Bellan E; Department of Pathology, Azienda Ospedale Università Padova, Padua, Italy., De Benedictis I; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Doni M; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Gambarotti M; Department of Pathology, IRCCS, Istituto Ortopedico Rizzoli, Bologna, Italy., Vincenzi B; Department of Medical Oncology, Università Campus Biomedico di Roma, Rome, Italy., Brunello A; Department of Oncology, Medical Oncology 1 Unit, Istituto Oncologico Veneto IOV, IRCCS, Padua, Italy., Baldi GG; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy., Palmerini E; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS, Istituto Ortopedico Rizzoli, Bologna, Italy., Pasquali S; Department of Applied Research and Technological Development, Molecular Pharmacology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Ciuffetti ME; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Varano V; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy., Cappello F; Department of Pathology, Azienda Ospedale Università Padova, Padua, Italy., Appolloni V; Italian Sarcoma Group, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Pastrello C; Division of Orthopaedic Surgery, Schroeder Arthritis Institute, Toronto, Canada., Jurisica I; Division of Orthopaedic Surgery, Schroeder Arthritis Institute, Toronto, Canada; Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, Toronto, Canada; Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Canada; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia., Gronchi A; Department of Sarcoma Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Stacchiotti S; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Casali PG; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy., Dei Tos AP; Surgical Pathology and Cytopathology Unit, Department of Medicine-DIMED, University of Padua School of Medicine, Padua, Italy., Maestro R; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy. Electronic address: rmaestro@cro.it.
Source: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc [Mod Pathol] 2025 Jan; Vol. 38 (1), pp. 100647. Date of Electronic Publication: 2024 Nov 02.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 8806605 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0285 (Electronic) Linking ISSN: 08933952 NLM ISO Abbreviation: Mod Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Proximal and Classic Epithelioid Sarcomas are Distinct Molecular Entities Defined by MYC/GATA3 and SOX17/Endothelial Markers, Respectively.
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  Data: <searchLink fieldCode="AU" term="%22Sigalotti+L%22">Sigalotti L</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Frezza+AM%22">Frezza AM</searchLink>; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sbaraglia+M%22">Sbaraglia M</searchLink>; Surgical Pathology and Cytopathology Unit, Department of Medicine-DIMED, University of Padua School of Medicine, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Del+Savio+E%22">Del Savio E</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Baldazzi+D%22">Baldazzi D</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Valenti+B%22">Valenti B</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Bellan+E%22">Bellan E</searchLink>; Department of Pathology, Azienda Ospedale Università Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22De+Benedictis+I%22">De Benedictis I</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Doni+M%22">Doni M</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Gambarotti+M%22">Gambarotti M</searchLink>; Department of Pathology, IRCCS, Istituto Ortopedico Rizzoli, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Vincenzi+B%22">Vincenzi B</searchLink>; Department of Medical Oncology, Università Campus Biomedico di Roma, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Brunello+A%22">Brunello A</searchLink>; Department of Oncology, Medical Oncology 1 Unit, Istituto Oncologico Veneto IOV, IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Baldi+GG%22">Baldi GG</searchLink>; Department of Medical Oncology, Hospital of Prato, Azienda USL Toscana Centro, Prato, Italy.<br /><searchLink fieldCode="AU" term="%22Palmerini+E%22">Palmerini E</searchLink>; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS, Istituto Ortopedico Rizzoli, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Pasquali+S%22">Pasquali S</searchLink>; Department of Applied Research and Technological Development, Molecular Pharmacology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ciuffetti+ME%22">Ciuffetti ME</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Varano+V%22">Varano V</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy.<br /><searchLink fieldCode="AU" term="%22Cappello+F%22">Cappello F</searchLink>; Department of Pathology, Azienda Ospedale Università Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Appolloni+V%22">Appolloni V</searchLink>; Italian Sarcoma Group, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pastrello+C%22">Pastrello C</searchLink>; Division of Orthopaedic Surgery, Schroeder Arthritis Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Jurisica+I%22">Jurisica I</searchLink>; Division of Orthopaedic Surgery, Schroeder Arthritis Institute, Toronto, Canada; Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, Toronto, Canada; Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Canada; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Gronchi+A%22">Gronchi A</searchLink>; Department of Sarcoma Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Stacchiotti+S%22">Stacchiotti S</searchLink>; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Casali+PG%22">Casali PG</searchLink>; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Haemato-Oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dei+Tos+AP%22">Dei Tos AP</searchLink>; Surgical Pathology and Cytopathology Unit, Department of Medicine-DIMED, University of Padua School of Medicine, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Maestro+R%22">Maestro R</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, Centro di Riferimento Oncologico di Aviano (CRO Aviano) IRCCS, National Cancer Institute, Aviano, Italy. Electronic address: rmaestro@cro.it.
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