Effects of Cimetidine and Dolutegravir on the Endogenous Drug-Drug Interaction Biomarkers for Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Protein 1 in Healthy Volunteers.
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| Title: | Effects of Cimetidine and Dolutegravir on the Endogenous Drug-Drug Interaction Biomarkers for Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Protein 1 in Healthy Volunteers. |
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| Authors: | Koishikawa T; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo City, Japan., Fujiwara K; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo City, Japan., Taskar K; Drug Metabolism and Pharmacokinetic, GSK, Stevenage, UK., Zamek-Gliszczynski MJ; Drug Metabolism and Pharmacokinetic, GSK, Collegeville, Pennsylvania, USA., Yoshida K; Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA., Chu X; Department of Pharmacokinetics, Dynamics, Metabolism, and Bioanalytics, Merck & Co., Inc., Rahway, New Jersey, USA., Hirabayashi H; Center of Excellence for Drug Metabolism, Pharmacokinetics and Modeling, Preclinical and Translational Sciences, Research, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Mao J; Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, USA., Rockich K; Drug Metabolism, Pharmacokinetics and Clinical Pharmacology, Incyte Research Institute, Wilmington, Delaware, USA., Takashima T; Laboratory for Safety Assessment & ADME, Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, Shizuoka, Japan., Yamaura Y; Pharmacokinetic Research Laboratories, Ono Pharmaceutical Co., Ltd., Osaka, Japan., Lai Y; Drug Metabolism Department, Gilead Sciences Inc., Foster City, California, USA., Tomoda Y; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo City, Japan., Kito T; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo City, Japan., Maeda K; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo City, Japan.; Faculty of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan., Furihata K; P-One Clinic, Keikokai Medical Corp, Tokyo, Japan., Sugiyama Y; Sugiyama Laboratory, RIKEN Baton Zone Program, RIKEN Cluster for Science, Technology and Innovation Hub, RIKEN, Yokohama, Kanagawa, Japan., Kusuhara H; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo City, Japan. |
| Source: | Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2025 Feb; Vol. 117 (2), pp. 523-533. Date of Electronic Publication: 2024 Nov 05. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1532-6535 |
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| DOI: | 10.1002/cpt.3482 |
