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Lesional senescent CD4+ T cells mediate bystander cytolysis and contribute to the skin pathology of human cutaneous leishmaniasis.

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Title: Lesional senescent CD4+ T cells mediate bystander cytolysis and contribute to the skin pathology of human cutaneous leishmaniasis.
Authors: Covre LP; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Division of Medicine, University College London, London, United Kingdom., Fantecelle CH; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil., Garcia de Moura R; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil., Oliveira Lopes P; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil., Sarmento IV; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil., Freire-de-Lima CG; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Decote-Ricardo D; Departamento de Veterinária, Universidade Federal Rural do Rio de Janeiro, Rio de Janeiro, Brazil., de Matos Guedes HL; Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., da Fonsceca-Martins AM; Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil., de Carvalho LP; Laboratório de Pesquisas Clínicas do Instituto Gonçalo Muniz, Fundação Oswaldo Cruz, Salvador, Brazil., de Carvalho EM; Laboratório de Pesquisas Clínicas do Instituto Gonçalo Muniz, Fundação Oswaldo Cruz, Salvador, Brazil., Mosser DM; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, United States., Falqueto A; Departamento de Medicina Social, Universidade Federal do Espírito Santo, Vitória, Brazil., Akbar AN; Division of Medicine, University College London, London, United Kingdom., Gomes DCO; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.
Source: Frontiers in immunology [Front Immunol] 2024 Oct 21; Vol. 15, pp. 1475146. Date of Electronic Publication: 2024 Oct 21 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Lesional senescent CD4<superscript>+</superscript> T cells mediate bystander cytolysis and contribute to the skin pathology of human cutaneous leishmaniasis.
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  Data: <searchLink fieldCode="AU" term="%22Covre+LP%22">Covre LP</searchLink>; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Division of Medicine, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Fantecelle+CH%22">Fantecelle CH</searchLink>; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.<br /><searchLink fieldCode="AU" term="%22Garcia+de+Moura+R%22">Garcia de Moura R</searchLink>; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+Lopes+P%22">Oliveira Lopes P</searchLink>; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.<br /><searchLink fieldCode="AU" term="%22Sarmento+IV%22">Sarmento IV</searchLink>; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.<br /><searchLink fieldCode="AU" term="%22Freire-de-Lima+CG%22">Freire-de-Lima CG</searchLink>; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Decote-Ricardo+D%22">Decote-Ricardo D</searchLink>; Departamento de Veterinária, Universidade Federal Rural do Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Matos+Guedes+HL%22">de Matos Guedes HL</searchLink>; Instituto de Microbiologia Professor Paulo de Goes, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.; Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Fonsceca-Martins+AM%22">da Fonsceca-Martins AM</searchLink>; Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Carvalho+LP%22">de Carvalho LP</searchLink>; Laboratório de Pesquisas Clínicas do Instituto Gonçalo Muniz, Fundação Oswaldo Cruz, Salvador, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Carvalho+EM%22">de Carvalho EM</searchLink>; Laboratório de Pesquisas Clínicas do Instituto Gonçalo Muniz, Fundação Oswaldo Cruz, Salvador, Brazil.<br /><searchLink fieldCode="AU" term="%22Mosser+DM%22">Mosser DM</searchLink>; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, United States.<br /><searchLink fieldCode="AU" term="%22Falqueto+A%22">Falqueto A</searchLink>; Departamento de Medicina Social, Universidade Federal do Espírito Santo, Vitória, Brazil.<br /><searchLink fieldCode="AU" term="%22Akbar+AN%22">Akbar AN</searchLink>; Division of Medicine, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gomes+DCO%22">Gomes DCO</searchLink>; Núcleo de Doenças Infecciosas, Universidade Federal do Espírito Santo, Vitória, Brazil.; Núcleo de Biotecnologia, Universidade Federal do Espírito Santo, Vitória, Brazil.
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