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Maturation and persistence of CAR T cells derived from human pluripotent stem cells via chemical inhibition of G9a/GLP.

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Title: Maturation and persistence of CAR T cells derived from human pluripotent stem cells via chemical inhibition of G9a/GLP.
Authors: Jing R; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Falchetti M; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Han T; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Najia M; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Hensch LT; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Meader E; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Lummertz da Rocha E; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, SC 88040-900, Brazil., Kononov M; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Wang S; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Bingham T; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Li Z; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Zhao Y; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Frenis K; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Kubaczka C; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Yang S; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Jha D; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Rodrigues-Luiz GF; Graduate Program of Pharmacology, Center for Biological Sciences, Federal University of Santa Catarina, Florianópolis, SC 88040-900, Brazil., Rowe RG; Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA., Schlaeger TM; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA., Maus MV; Cellular Immunotherapy Program, Massachusetts General Hospital Cancer Center, Charlestown, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA., North TE; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Developmental and Regenerative Biology Program, Harvard Medical School, Boston, MA 02115, USA., Zon LI; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA., Daley GQ; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: george.daley@childrens.harvard.edu.
Source: Cell stem cell [Cell Stem Cell] 2025 Jan 02; Vol. 32 (1), pp. 71-85.e5. Date of Electronic Publication: 2024 Nov 05.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Maturation and persistence of CAR T cells derived from human pluripotent stem cells via chemical inhibition of G9a/GLP.
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  Data: <searchLink fieldCode="AU" term="%22Jing+R%22">Jing R</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Falchetti+M%22">Falchetti M</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Han+T%22">Han T</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Najia+M%22">Najia M</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Hensch+LT%22">Hensch LT</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Meader+E%22">Meader E</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Lummertz+da+Rocha+E%22">Lummertz da Rocha E</searchLink>; Department of Microbiology, Immunology and Parasitology, Federal University of Santa Catarina, Florianópolis, SC 88040-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Kononov+M%22">Kononov M</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Bingham+T%22">Bingham T</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Frenis+K%22">Frenis K</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Kubaczka+C%22">Kubaczka C</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Jha+D%22">Jha D</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Rodrigues-Luiz+GF%22">Rodrigues-Luiz GF</searchLink>; Graduate Program of Pharmacology, Center for Biological Sciences, Federal University of Santa Catarina, Florianópolis, SC 88040-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Rowe+RG%22">Rowe RG</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Schlaeger+TM%22">Schlaeger TM</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Maus+MV%22">Maus MV</searchLink>; Cellular Immunotherapy Program, Massachusetts General Hospital Cancer Center, Charlestown, MA 02114, USA; Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22North+TE%22">North TE</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Developmental and Regenerative Biology Program, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Zon+LI%22">Zon LI</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Daley+GQ%22">Daley GQ</searchLink>; Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: george.daley@childrens.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%22101311472%22">Cell stem cell</searchLink> [Cell Stem Cell] 2025 Jan 02; Vol. 32 (1), pp. 71-85.e5. <i>Date of Electronic Publication: </i>2024 Nov 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101311472 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-9777 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218759777%22">18759777 </searchLink><i>NLM ISO Abbreviation: </i>Cell Stem Cell <i>Subsets: </i>MEDLINE
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