Systematic analysis of natural topoisomerase I inhibitors from Forsythiae Fructus by ultrafiltration-UPLC-ESI-MS/MS, pharmacophore modelling, and molecular dynamics simulation.
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| Title: | Systematic analysis of natural topoisomerase I inhibitors from Forsythiae Fructus by ultrafiltration-UPLC-ESI-MS/MS, pharmacophore modelling, and molecular dynamics simulation. |
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| Authors: | Wang T; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China., Tan N; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China., Lu J; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China., Li Z; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China., Wang H; College of Computer Science and Technology, Baoji University of Arts and Sciences, Baoji, China., Hu J; College of Electronic and Electrical Engineering, Baoji University of Arts and Sciences, Baoji, China., Zhang S; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China., Qi J; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A & F University, Yangling, China., Wang X; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China., Wang L; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China. |
| Source: | Natural product research [Nat Prod Res] 2026 Mar; Vol. 40 (5), pp. 1327-1337. Date of Electronic Publication: 2024 Nov 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39506523 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Systematic analysis of natural topoisomerase I inhibitors from Forsythiae Fructus by ultrafiltration-UPLC-ESI-MS/MS, pharmacophore modelling, and molecular dynamics simulation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Tan+N%22">Tan N</searchLink>; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; College of Computer Science and Technology, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Hu+J%22">Hu J</searchLink>; College of Electronic and Electrical Engineering, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Qi+J%22">Qi J</searchLink>; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A & F University, Yangling, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Key Laboratory of Phytochemistry, College of Chemistry and Chemical Engineering, Baoji University of Arts and Sciences, Baoji, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101167924%22">Natural product research</searchLink> [Nat Prod Res] 2026 Mar; Vol. 40 (5), pp. 1327-1337. <i>Date of Electronic Publication: </i>2024 Nov 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis+Health+Sciences%22">Taylor & Francis Health Sciences </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101167924 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1478-6427 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214786419%22">14786419 </searchLink><i>NLM ISO Abbreviation: </i>Nat Prod Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39506523 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/14786419.2024.2425055 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1327 Titles: – TitleFull: Systematic analysis of natural topoisomerase I inhibitors from Forsythiae Fructus by ultrafiltration-UPLC-ESI-MS/MS, pharmacophore modelling, and molecular dynamics simulation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wang T – PersonEntity: Name: NameFull: Tan N – PersonEntity: Name: NameFull: Lu J – PersonEntity: Name: NameFull: Li Z – PersonEntity: Name: NameFull: Wang H – PersonEntity: Name: NameFull: Hu J – PersonEntity: Name: NameFull: Zhang S – PersonEntity: Name: NameFull: Qi J – PersonEntity: Name: NameFull: Wang X – PersonEntity: Name: NameFull: Wang L IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2026 Mar Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1478-6427 Numbering: – Type: volume Value: 40 – Type: issue Value: 5 Titles: – TitleFull: Natural product research Type: main |
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