A 40-week phase 2B randomized, multicenter, double-blind, placebo-controlled study evaluating the safety and efficacy of memantine in amyotrophic lateral sclerosis.
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| Title: | A 40-week phase 2B randomized, multicenter, double-blind, placebo-controlled study evaluating the safety and efficacy of memantine in amyotrophic lateral sclerosis. |
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| Authors: | Bhai S; University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Neuromuscular Center, Institute for Exercise and Environmental Medicine, Texas Health Dallas, Dallas, Texas, USA., Levine T; Honor Health, Scottsdale, Arizona, USA., Moore D; Calico Consulting, Livermore, California, USA., Bowser R; Barrow Neurological Institute, Phoenix, Arizona, USA., Heim AJ; University of Kansas Medical Center, Kansas City, Kansas, USA., Walsh M; University of Kansas Medical Center, Kansas City, Kansas, USA., Shibani A; Nerve and Muscle Center of Texas, Houston, Texas, USA., Simmons Z; Penn State Hershey Medical Center, Hershey, Pennsylvania, USA., Grogan J; Penn State Hershey Medical Center, Hershey, Pennsylvania, USA., Goyal NA; University of California, Irvine, California, USA., Govindarajan R; University of Missouri, Columbia, Missouri, USA., Hussain Y; Austin Neuromuscular Center, Austin, Texas, USA.; University of Texas Dell Medical School, Austin, Texas, USA., Papsdorf T; Access TeleCare, Dallas, Texas, USA., Schwasinger-Schmidt T; University of Kansas School of Medicine-Wichita, Wichita, Kansas, USA., Olney N; Providence Brain and Spine Institute, Portland, Oregon, USA., Goslin K; Providence Brain and Spine Institute, Portland, Oregon, USA., Pulley M; University of Florida College of Medicine Jacksonville, Jacksonville, Florida, USA., Kasarskis E; University of Kentucky, Lexington, Kentucky, USA., Weiss M; University of Washington, Seattle, Washington, USA., Katz SW; Syneos Health, Morrisville, North Carolina, USA., Moser S; University of Missouri, Columbia, Missouri, USA., Jabari D; Cedars-Sinai Medical Center, Los Angeles, California, USA., Jawdat O; University of Kansas Medical Center, Kansas City, Kansas, USA., Statland J; University of Kansas Medical Center, Kansas City, Kansas, USA., Dimachkie MM; University of Kansas Medical Center, Kansas City, Kansas, USA., Barohn R; University of Missouri, Columbia, Missouri, USA. |
| Corporate Authors: | Neuromuscular Study Group and Western ALS Consortium Memantine ALS Study Group |
| Source: | Muscle & nerve [Muscle Nerve] 2025 Jan; Vol. 71 (1), pp. 63-72. Date of Electronic Publication: 2024 Nov 07. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II |
| Journal Info: | Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39511965 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A 40-week phase 2B randomized, multicenter, double-blind, placebo-controlled study evaluating the safety and efficacy of memantine in amyotrophic lateral sclerosis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bhai+S%22">Bhai S</searchLink>; University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Neuromuscular Center, Institute for Exercise and Environmental Medicine, Texas Health Dallas, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Levine+T%22">Levine T</searchLink>; Honor Health, Scottsdale, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Moore+D%22">Moore D</searchLink>; Calico Consulting, Livermore, California, USA.<br /><searchLink fieldCode="AU" term="%22Bowser+R%22">Bowser R</searchLink>; Barrow Neurological Institute, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Heim+AJ%22">Heim AJ</searchLink>; University of Kansas Medical Center, Kansas City, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Walsh+M%22">Walsh M</searchLink>; University of Kansas Medical Center, Kansas City, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Shibani+A%22">Shibani A</searchLink>; Nerve and Muscle Center of Texas, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Simmons+Z%22">Simmons Z</searchLink>; Penn State Hershey Medical Center, Hershey, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Grogan+J%22">Grogan J</searchLink>; Penn State Hershey Medical Center, Hershey, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Goyal+NA%22">Goyal NA</searchLink>; University of California, Irvine, California, USA.<br /><searchLink fieldCode="AU" term="%22Govindarajan+R%22">Govindarajan R</searchLink>; University of Missouri, Columbia, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Hussain+Y%22">Hussain Y</searchLink>; Austin Neuromuscular Center, Austin, Texas, USA.; University of Texas Dell Medical School, Austin, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Papsdorf+T%22">Papsdorf T</searchLink>; Access TeleCare, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Schwasinger-Schmidt+T%22">Schwasinger-Schmidt T</searchLink>; University of Kansas School of Medicine-Wichita, Wichita, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Olney+N%22">Olney N</searchLink>; Providence Brain and Spine Institute, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Goslin+K%22">Goslin K</searchLink>; Providence Brain and Spine Institute, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Pulley+M%22">Pulley M</searchLink>; University of Florida College of Medicine Jacksonville, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Kasarskis+E%22">Kasarskis E</searchLink>; University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+M%22">Weiss M</searchLink>; University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Katz+SW%22">Katz SW</searchLink>; Syneos Health, Morrisville, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Moser+S%22">Moser S</searchLink>; University of Missouri, Columbia, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Jabari+D%22">Jabari D</searchLink>; Cedars-Sinai Medical Center, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Jawdat+O%22">Jawdat O</searchLink>; University of Kansas Medical Center, Kansas City, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Statland+J%22">Statland J</searchLink>; University of Kansas Medical Center, Kansas City, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Dimachkie+MM%22">Dimachkie MM</searchLink>; University of Kansas Medical Center, Kansas City, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Barohn+R%22">Barohn R</searchLink>; University of Missouri, Columbia, Missouri, USA. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Neuromuscular+Study+Group+and+Western+ALS+Consortium+Memantine+ALS+Study+Group%22">Neuromuscular Study Group and Western ALS Consortium Memantine ALS Study Group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227803146%22">Muscle & nerve</searchLink> [Muscle Nerve] 2025 Jan; Vol. 71 (1), pp. 63-72. <i>Date of Electronic Publication: </i>2024 Nov 07. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%22">John Wiley & Sons </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7803146 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220148639X%22">0148639X </searchLink><i>NLM ISO Abbreviation: </i>Muscle Nerve <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39511965 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mus.28287 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 63 Titles: – TitleFull: A 40-week phase 2B randomized, multicenter, double-blind, placebo-controlled study evaluating the safety and efficacy of memantine in amyotrophic lateral sclerosis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bhai S – PersonEntity: Name: NameFull: Levine T – PersonEntity: Name: NameFull: Moore D – PersonEntity: Name: NameFull: Bowser R – PersonEntity: Name: NameFull: Heim AJ – PersonEntity: Name: NameFull: Walsh M – PersonEntity: Name: NameFull: Shibani A – PersonEntity: Name: NameFull: Simmons Z – PersonEntity: Name: NameFull: Grogan J – PersonEntity: Name: NameFull: Goyal NA – PersonEntity: Name: NameFull: Govindarajan R – PersonEntity: Name: NameFull: Hussain Y – PersonEntity: Name: NameFull: Papsdorf T – PersonEntity: Name: NameFull: Schwasinger-Schmidt T – PersonEntity: Name: NameFull: Olney N – PersonEntity: Name: NameFull: Goslin K – PersonEntity: Name: NameFull: Pulley M – PersonEntity: Name: NameFull: Kasarskis E – PersonEntity: Name: NameFull: Weiss M – PersonEntity: Name: NameFull: Katz SW – PersonEntity: Name: NameFull: Moser S – PersonEntity: Name: NameFull: Jabari D – PersonEntity: Name: NameFull: Jawdat O – PersonEntity: Name: NameFull: Statland J – PersonEntity: Name: NameFull: Dimachkie MM – PersonEntity: Name: NameFull: Barohn R IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2025 Jan Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1097-4598 Numbering: – Type: volume Value: 71 – Type: issue Value: 1 Titles: – TitleFull: Muscle & nerve Type: main |
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