The role of inflammation induced by necroptosis in the development of fibrosis and liver cancer in novel knockin mouse models fed a western diet.

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Title: The role of inflammation induced by necroptosis in the development of fibrosis and liver cancer in novel knockin mouse models fed a western diet.
Authors: Selvarani R; Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Nguyen HM; Nutritional Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Pazhanivel N; Department of Veterinary Pathology, TANUVAS, Chennai City, Tamilnadu, India., Raman M; Saveetha Medical College, Chennai City, Tamilnadu, India., Lee S; Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Wolf RF; Oklahoma Veteran Affairs Medical Center, Oklahoma City, OK, USA., Deepa SS; Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.; Stephenson Cancer Center, Oklahoma City, OK, USA.; Oklahoma Center for Geroscience & Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Richardson A; Biochemistry & Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. arlan-richardson@ouhsc.edu.; Stephenson Cancer Center, Oklahoma City, OK, USA. arlan-richardson@ouhsc.edu.; Oklahoma Center for Geroscience & Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. arlan-richardson@ouhsc.edu.; Oklahoma Veteran Affairs Medical Center, Oklahoma City, OK, USA. arlan-richardson@ouhsc.edu.
Source: GeroScience [Geroscience] 2025 Jun; Vol. 47 (3), pp. 2973-2994. Date of Electronic Publication: 2024 Nov 08.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2509-2723
DOI:10.1007/s11357-024-01418-3