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Exploring the Chemopreventive Effect of Medication on Gene Expression Linked to Colorectal Cancer: An Observational and Mendelian Randomization Analysis in Healthy Colon Mucosa.

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Title: Exploring the Chemopreventive Effect of Medication on Gene Expression Linked to Colorectal Cancer: An Observational and Mendelian Randomization Analysis in Healthy Colon Mucosa.
Authors: Moratalla-Navarro F; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine and Health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), 08907 L'Hospitalet de Llobregat, Barcelona, Spain., Carreras-Torres R; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Group of Digestive Diseases and Microbiota, Institute d'Investigació Biomèdica de Girona Dr Josep Trueta-IDIBGI, 17190 Salt, Girona, Spain., Díez-Obrero V; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Department of Clinical Sciences, Faculty of Medicine and Health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), 08907 L'Hospitalet de Llobregat, Barcelona, Spain., Devall M; Department of Family Medicine, University of Virginia, Charlottesville, VA 22903, USA., Obón-Santacana M; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain., Díez-Villanueva A; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain., Guinó E; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain., Casey G; Department of Genome Sciences, University of Virginia, Charlottesville, VA 22903, USA., Li L; Department of Family Medicine, University of Virginia, Charlottesville, VA 22903, USA., Moreno V; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine and Health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
Source: International journal of molecular sciences [Int J Mol Sci] 2024 Oct 23; Vol. 25 (21). Date of Electronic Publication: 2024 Oct 23.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exploring the Chemopreventive Effect of Medication on Gene Expression Linked to Colorectal Cancer: An Observational and Mendelian Randomization Analysis in Healthy Colon Mucosa.
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  Data: <searchLink fieldCode="AU" term="%22Moratalla-Navarro+F%22">Moratalla-Navarro F</searchLink>; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine and Health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), 08907 L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Carreras-Torres+R%22">Carreras-Torres R</searchLink>; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Group of Digestive Diseases and Microbiota, Institute d'Investigació Biomèdica de Girona Dr Josep Trueta-IDIBGI, 17190 Salt, Girona, Spain.<br /><searchLink fieldCode="AU" term="%22Díez-Obrero+V%22">Díez-Obrero V</searchLink>; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Department of Clinical Sciences, Faculty of Medicine and Health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), 08907 L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Devall+M%22">Devall M</searchLink>; Department of Family Medicine, University of Virginia, Charlottesville, VA 22903, USA.<br /><searchLink fieldCode="AU" term="%22Obón-Santacana+M%22">Obón-Santacana M</searchLink>; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Díez-Villanueva+A%22">Díez-Villanueva A</searchLink>; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Guinó+E%22">Guinó E</searchLink>; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Casey+G%22">Casey G</searchLink>; Department of Genome Sciences, University of Virginia, Charlottesville, VA 22903, USA.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Family Medicine, University of Virginia, Charlottesville, VA 22903, USA.<br /><searchLink fieldCode="AU" term="%22Moreno+V%22">Moreno V</searchLink>; Oncology Data Analytics Program, Catalan Institute of Oncology, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Colorectal Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology (ONCOBELL) Program, Bellvitge Biomedical Research Institute, 08908 L'Hospitalet de Llobregat, Barcelona, Spain.; Consortium for Biomedical Research in Epidemiology and Public Health, 28029 Madrid, Spain.; Department of Clinical Sciences, Faculty of Medicine and Health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2024 Oct 23; Vol. 25 (21). <i>Date of Electronic Publication: </i>2024 Oct 23.
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