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Identification of a 5-Plex Cytokine Signature that Differentiates Patients with Multiple Systemic Inflammatory Diseases.

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Title: Identification of a 5-Plex Cytokine Signature that Differentiates Patients with Multiple Systemic Inflammatory Diseases.
Authors: Hoste L; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium., Meertens B; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium., Ogunjimi B; Rheumatology Department, Antwerp Hospital Network, Antwerp, Belgium.; Division of Pediatric Rheumatology, Antwerp University Hospital, Edegem, Belgium.; Antwerp Center for Pediatric Rheumatology and Autoinflammatory Diseases, Antwerp, Belgium.; Division of Pediatric Rheumatology, Brussels University Hospital, Jette, Belgium.; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute (VAXINFECTIO) ,Centre for Health Economics Research and Modeling Infectious Diseases (CHERMID), University of Antwerp, Antwerp, Belgium., Sabato V; Department of Immunology, Allergology, and Rheumatology, Antwerp University Hospital, Edegem, Belgium., Guerti K; Department of Clinical Chemistry, Antwerp University Hospital, Edegem, Belgium., van der Hilst J; Department of Infectious Diseases and Immune Pathology, Jessa General Hospital, Hasselt, Belgium.; Limburg Clinical Research Center, Hasselt University, Hasselt, Belgium., Bogie J; Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Hasselt, Belgium.; University MS Centre, Hasselt University, Hasselt, Belgium., Joos R; Division of Pediatric Rheumatology, Antwerp University Hospital, Edegem, Belgium.; Department of Immunology, Allergology, and Rheumatology, Antwerp University Hospital, Edegem, Belgium.; Department of Pediatric Rheumatology, Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN-RITA) Center, Ghent, Belgium., Claes K; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium., Debacker V; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium., Janssen F; Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium., Tavernier SJ; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.; Unit of Molecular Signal Transduction in Inflammation, VIB-UGent Center for Inflammation Research, Ghent, Belgium., Jacques P; Department of Rheumatology, University Hospital Ghent, Ghent, Belgium., Callens S; Department of General Internal Medicine, Ghent University Hospital, Ghent, Belgium., Dehoorne J; Department of Pediatric Rheumatology, Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN-RITA) Center, Ghent, Belgium., Haerynck F; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium. filomeen.haerynck@uzgent.be.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium. filomeen.haerynck@uzgent.be.
Source: Inflammation [Inflammation] 2025 Aug; Vol. 48 (4), pp. 2182-2197. Date of Electronic Publication: 2024 Nov 12.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2576 (Electronic) Linking ISSN: 03603997 NLM ISO Abbreviation: Inflammation Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Identification of a 5-Plex Cytokine Signature that Differentiates Patients with Multiple Systemic Inflammatory Diseases.
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  Data: <searchLink fieldCode="AU" term="%22Hoste+L%22">Hoste L</searchLink>; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Meertens+B%22">Meertens B</searchLink>; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Ogunjimi+B%22">Ogunjimi B</searchLink>; Rheumatology Department, Antwerp Hospital Network, Antwerp, Belgium.; Division of Pediatric Rheumatology, Antwerp University Hospital, Edegem, Belgium.; Antwerp Center for Pediatric Rheumatology and Autoinflammatory Diseases, Antwerp, Belgium.; Division of Pediatric Rheumatology, Brussels University Hospital, Jette, Belgium.; Antwerp Center for Translational Immunology and Virology (ACTIV), Vaccine and Infectious Disease Institute (VAXINFECTIO) ,Centre for Health Economics Research and Modeling Infectious Diseases (CHERMID), University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Sabato+V%22">Sabato V</searchLink>; Department of Immunology, Allergology, and Rheumatology, Antwerp University Hospital, Edegem, Belgium.<br /><searchLink fieldCode="AU" term="%22Guerti+K%22">Guerti K</searchLink>; Department of Clinical Chemistry, Antwerp University Hospital, Edegem, Belgium.<br /><searchLink fieldCode="AU" term="%22van+der+Hilst+J%22">van der Hilst J</searchLink>; Department of Infectious Diseases and Immune Pathology, Jessa General Hospital, Hasselt, Belgium.; Limburg Clinical Research Center, Hasselt University, Hasselt, Belgium.<br /><searchLink fieldCode="AU" term="%22Bogie+J%22">Bogie J</searchLink>; Department of Immunology and Infection, Biomedical Research Institute, Hasselt University, Hasselt, Belgium.; University MS Centre, Hasselt University, Hasselt, Belgium.<br /><searchLink fieldCode="AU" term="%22Joos+R%22">Joos R</searchLink>; Division of Pediatric Rheumatology, Antwerp University Hospital, Edegem, Belgium.; Department of Immunology, Allergology, and Rheumatology, Antwerp University Hospital, Edegem, Belgium.; Department of Pediatric Rheumatology, Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN-RITA) Center, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Claes+K%22">Claes K</searchLink>; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Debacker+V%22">Debacker V</searchLink>; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Janssen+F%22">Janssen F</searchLink>; Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Tavernier+SJ%22">Tavernier SJ</searchLink>; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.; Center for Medical Genetics, Ghent University Hospital, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.; Unit of Molecular Signal Transduction in Inflammation, VIB-UGent Center for Inflammation Research, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Jacques+P%22">Jacques P</searchLink>; Department of Rheumatology, University Hospital Ghent, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Callens+S%22">Callens S</searchLink>; Department of General Internal Medicine, Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Dehoorne+J%22">Dehoorne J</searchLink>; Department of Pediatric Rheumatology, Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases (ERN-RITA) Center, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Haerynck+F%22">Haerynck F</searchLink>; Primary Immune Deficiency Research Laboratory, Department of Internal Diseases and Pediatrics, Centre for Primary Immunodeficiency Ghent, Jeffrey Modell Diagnosis and Research Centre, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium. filomeen.haerynck@uzgent.be.; Department of Internal Medicine and Pediatrics, Division of Pediatric Pulmonology, Infectious Diseases and Inborn Errors of Immunity ,Ghent University Hospital, European Reference Network for Rare Immunodeficiency, Autoinflammatory and Autoimmune Diseases Network (ERN-RITA) Center, Ghent, Belgium. filomeen.haerynck@uzgent.be.
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  Data: <searchLink fieldCode="JN" term="%227600105%22">Inflammation</searchLink> [Inflammation] 2025 Aug; Vol. 48 (4), pp. 2182-2197. <i>Date of Electronic Publication: </i>2024 Nov 12.
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