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Age-associated metabolic and epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes.

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Title: Age-associated metabolic and epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes.
Authors: Santos F; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal., Correia M; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal., Dias R; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal., Bola B; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal., Noberini R; Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy., Ferreira RS; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal., Trigo D; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal., Domingues P; Mass Spectrometry Center, Department of Chemistry, University of Aveiro, Aveiro, Portugal.; LAQV/REQUIMTE, University of Aveiro, Aveiro, Portugal., Teixeira J; CNC-UC, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; CIBB, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Cantanhede, Portugal., Bonaldi T; Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.; Department of Oncology and Hematology-Oncology, University of Milano, Milan, Italy., Oliveira PJ; CNC-UC, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; CIBB, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Cantanhede, Portugal., Bär C; Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School (MHH), Hannover, Germany.; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany., de Jesus BB; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal., Nóbrega-Pereira S; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.
Source: Aging cell [Aging Cell] 2025 Feb; Vol. 24 (2), pp. e14371. Date of Electronic Publication: 2024 Nov 14.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Age-associated metabolic and epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes.
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  Data: <searchLink fieldCode="AU" term="%22Santos+F%22">Santos F</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Correia+M%22">Correia M</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Dias+R%22">Dias R</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Bola+B%22">Bola B</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Noberini+R%22">Noberini R</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ferreira+RS%22">Ferreira RS</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Trigo+D%22">Trigo D</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Domingues+P%22">Domingues P</searchLink>; Mass Spectrometry Center, Department of Chemistry, University of Aveiro, Aveiro, Portugal.; LAQV/REQUIMTE, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Teixeira+J%22">Teixeira J</searchLink>; CNC-UC, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; CIBB, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Cantanhede, Portugal.<br /><searchLink fieldCode="AU" term="%22Bonaldi+T%22">Bonaldi T</searchLink>; Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.; Department of Oncology and Hematology-Oncology, University of Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Oliveira+PJ%22">Oliveira PJ</searchLink>; CNC-UC, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.; CIBB, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Cantanhede, Portugal.<br /><searchLink fieldCode="AU" term="%22Bär+C%22">Bär C</searchLink>; Institute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School (MHH), Hannover, Germany.; Fraunhofer Institute for Toxicology and Experimental Medicine (ITEM), Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22de+Jesus+BB%22">de Jesus BB</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Nóbrega-Pereira+S%22">Nóbrega-Pereira S</searchLink>; Department of Medical Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal.
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              Text: 2025 Feb
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