Comparative efficacy, toxicity, and insulin-suppressive effects of simvastatin and pravastatin in fatty acid-challenged mouse insulinoma MIN6 β-cell model.

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Title: Comparative efficacy, toxicity, and insulin-suppressive effects of simvastatin and pravastatin in fatty acid-challenged mouse insulinoma MIN6 β-cell model.
Authors: Arefanian H; Immunology and Microbiology Department, Dasman Diabetes Institute, Kuwait City, Kuwait., Sindhu S; Immunology and Microbiology Department, Dasman Diabetes Institute, Kuwait City, Kuwait.; Animal and Imaging Core Facility, Dasman Diabetes Institute, Kuwait City, Kuwait., Al-Rashed F; Immunology and Microbiology Department, Dasman Diabetes Institute, Kuwait City, Kuwait., Alzaid F; Department of Bioenergetics and Neurometabolism, Dasman Diabetes Institute, Kuwait City, Kuwait.; Institut Necker Enfants Malades (INEM), French Institute of Health and Medical Research (INSERM), Immunity and Metabolism of Diabetes (IMMEDIAB), Université de Paris Cité, Paris, France., Al Madhoun A; Animal and Imaging Core Facility, Dasman Diabetes Institute, Kuwait City, Kuwait.; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait., Qaddoumi M; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Kuwait City, Kuwait.; Department of Pharmacology and Therapeutics, College of Pharmacy, Kuwait University, Kuwait City, Kuwait., Bahman F; Immunology and Microbiology Department, Dasman Diabetes Institute, Kuwait City, Kuwait., Williams MR; Department of Bioenergetics and Neurometabolism, Dasman Diabetes Institute, Kuwait City, Kuwait., Albeloushi S; Immunology and Microbiology Department, Dasman Diabetes Institute, Kuwait City, Kuwait., Almansour N; Immunology and Microbiology Department, Dasman Diabetes Institute, Kuwait City, Kuwait., Ahmad R; Immunology and Microbiology Department, Dasman Diabetes Institute, Kuwait City, Kuwait., Al-Mulla F; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Kuwait City, Kuwait.
Source: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2024 Oct 31; Vol. 15, pp. 1383448. Date of Electronic Publication: 2024 Oct 31 (Print Publication: 2024).
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-2392
DOI:10.3389/fendo.2024.1383448