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Topical application of the Hedgehog inhibitor patidegib in patients with Gorlin syndrome: a phase II trial.

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Title: Topical application of the Hedgehog inhibitor patidegib in patients with Gorlin syndrome: a phase II trial.
Authors: Lear JT; Department of Dermatology, Manchester Royal Infirmary, Manchester, UK.; Manchester Academic Health Science Centre, University of Manchester, Manchester, UK., Harwood CA; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK., Hasan Z; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK., Kentley J; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK., Thomson J; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK., Khoo A; Department of Dermatology, Manchester Royal Infirmary, Manchester, UK.; Manchester Academic Health Science Centre, University of Manchester, Manchester, UK., Alderman A; PellePharm, Inc., San Francisco, CA, USA., DeSouza M; PellePharm, Inc., San Francisco, CA, USA., Epstein EH Jr; PellePharm, Inc., San Francisco, CA, USA., Kochendoerfer GG; PellePharm, Inc., San Francisco, CA, USA., Tang JY; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.
Source: The British journal of dermatology [Br J Dermatol] 2025 Mar 18; Vol. 192 (4), pp. 611-617.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Topical application of the Hedgehog inhibitor patidegib in patients with Gorlin syndrome: a phase II trial.
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  Data: <searchLink fieldCode="AU" term="%22Lear+JT%22">Lear JT</searchLink>; Department of Dermatology, Manchester Royal Infirmary, Manchester, UK.; Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Harwood+CA%22">Harwood CA</searchLink>; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hasan+Z%22">Hasan Z</searchLink>; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kentley+J%22">Kentley J</searchLink>; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Thomson+J%22">Thomson J</searchLink>; Royal London Hospital, Barts Health NHS Trust/Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Khoo+A%22">Khoo A</searchLink>; Department of Dermatology, Manchester Royal Infirmary, Manchester, UK.; Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Alderman+A%22">Alderman A</searchLink>; PellePharm, Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22DeSouza+M%22">DeSouza M</searchLink>; PellePharm, Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Epstein+EH+Jr%22">Epstein EH Jr</searchLink>; PellePharm, Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kochendoerfer+GG%22">Kochendoerfer GG</searchLink>; PellePharm, Inc., San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tang+JY%22">Tang JY</searchLink>; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%220004041%22">The British journal of dermatology</searchLink> [Br J Dermatol] 2025 Mar 18; Vol. 192 (4), pp. 611-617.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0004041 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2133 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070963%22">00070963 </searchLink><i>NLM ISO Abbreviation: </i>Br J Dermatol <i>Subsets: </i>MEDLINE
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        Value: 10.1093/bjd/ljae444
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              Text: 2025 Mar 18
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