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Shock prediction with dipeptidyl peptidase-3 and renin (SPiDeR) in hypoxemic patients with COVID-19.

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Title: Shock prediction with dipeptidyl peptidase-3 and renin (SPiDeR) in hypoxemic patients with COVID-19.
Authors: Busse LW; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Emory University, Atlanta, GA, USA; Emory Critical Care Center, Emory Healthcare, Atlanta, GA, USA., Teixeira JP; Division of Nephrology, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA. Electronic address: jteixeira@salud.unm.edu., Schaich CL; Hypertension and Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Ten Lohuis CC; Emory Critical Care Center, Emory Healthcare, Atlanta, GA, USA., Nielsen ND; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA; Section of Transfusion Medicine and Therapeutic Pathology, Department of Pathology, University of New Mexico School of Medicine, Albuquerque, NM, USA., Sturek JM; Division of Pulmonary and Critical Care, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA., Merck LH; Department of Emergency Medicine, Virginia Commonwealth University, Richmond, VA, USA., Self WH; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Puskarich MA; Department of Emergency Medicine, Hennepin Healthcare, Minneapolis, MN, USA., Khan A; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Oregon Health and Science University, Portland, OR, USA., Semler MW; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Moskowitz A; Division of Critical Care, Montefiore Medical Center, The Bronx, NY, USA., Hager DN; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Duggal A; Department of Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA., Rice TW; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Ginde AA; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA., Tiffany BR; Chandler Regional Medical Center, Chandler, AZ, USA., Iovine NM; University of Florida Health, Gainesville, FL, USA., Chen P; Women's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Safdar B; Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA., Gibbs KW; Department of Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Javaheri A; Department of Medicine, Washington University, Saint Louis, MO, USA., de Wit M; Department of Medicine, Virginia Commonwealth University, Richmond, VA, USA., Harkins MS; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA., Joly MM; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA., Collins SP; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
Corporate Authors: ACTIV-4 Host Tissue Investigators
Source: Journal of critical care [J Crit Care] 2025 Feb; Vol. 85, pp. 154950. Date of Electronic Publication: 2024 Nov 14.
Publication Type: Journal Article
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 8610642 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8615 (Electronic) Linking ISSN: 08839441 NLM ISO Abbreviation: J Crit Care Subsets: MEDLINE
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Electronic address: jteixeira@salud.unm.edu.<br /><searchLink fieldCode="AU" term="%22Schaich+CL%22">Schaich CL</searchLink>; Hypertension and Vascular Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ten+Lohuis+CC%22">Ten Lohuis CC</searchLink>; Emory Critical Care Center, Emory Healthcare, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Nielsen+ND%22">Nielsen ND</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA; Section of Transfusion Medicine and Therapeutic Pathology, Department of Pathology, University of New Mexico School of Medicine, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Sturek+JM%22">Sturek JM</searchLink>; Division of Pulmonary and Critical Care, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Merck+LH%22">Merck LH</searchLink>; Department of Emergency Medicine, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Self+WH%22">Self WH</searchLink>; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Puskarich+MA%22">Puskarich MA</searchLink>; Department of Emergency Medicine, Hennepin Healthcare, Minneapolis, MN, USA.<br /><searchLink fieldCode="AU" term="%22Khan+A%22">Khan A</searchLink>; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Oregon Health and Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Semler+MW%22">Semler MW</searchLink>; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Moskowitz+A%22">Moskowitz A</searchLink>; Division of Critical Care, Montefiore Medical Center, The Bronx, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hager+DN%22">Hager DN</searchLink>; Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Duggal+A%22">Duggal A</searchLink>; Department of Critical Care Medicine, Integrated Hospital Care Institute, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Rice+TW%22">Rice TW</searchLink>; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Ginde+AA%22">Ginde AA</searchLink>; Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Tiffany+BR%22">Tiffany BR</searchLink>; Chandler Regional Medical Center, Chandler, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Iovine+NM%22">Iovine NM</searchLink>; University of Florida Health, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Chen+P%22">Chen P</searchLink>; Women's Guild Lung Institute, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Safdar+B%22">Safdar B</searchLink>; Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Gibbs+KW%22">Gibbs KW</searchLink>; Department of Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Javaheri+A%22">Javaheri A</searchLink>; Department of Medicine, Washington University, Saint Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22de+Wit+M%22">de Wit M</searchLink>; Department of Medicine, Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Harkins+MS%22">Harkins MS</searchLink>; Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Joly+MM%22">Joly MM</searchLink>; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Collins+SP%22">Collins SP</searchLink>; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute of Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
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