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Sumac liposomes/mesenchymal stem cells fight methotrexate-induced nephrotoxicity in rats via regulating Nrf-2/Keap-1/HO-1 and apoptotic signaling pathways.

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Title: Sumac liposomes/mesenchymal stem cells fight methotrexate-induced nephrotoxicity in rats via regulating Nrf-2/Keap-1/HO-1 and apoptotic signaling pathways.
Authors: Zahran EM; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia, Egypt., Mohyeldin RH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Deraya University, New Minia, Egypt.; Deraya Center for Scientific Research, Deraya University, New Minia, Egypt., Refaat H; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, USA., Abou-Zied HA; Department of Medicinal Chemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt., ElNaggar MH; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt., Abbas GM; Department of Pharmacognosy, Faculty of Pharmacy, Horus University- Egypt (HUE), New Damietta, Egypt., Maher SA; Department of Biochemistry, Faculty of Pharmacy, New Valley University, El-kharga City, Egypt., Saber EA; Department of Medical Science (Histology and Cell Biology), Faculty of Pharmacy, Deraya University, Minia, Egypt., Zarka MA; Department of College of Pharmacy, The Islamic University, Najaf, Iraq., Elrehany MA; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt., Abdelmohsen UR; Deraya Center for Scientific Research, Deraya University, New Minia, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Source: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2025 Jan; Vol. 358 (1), pp. e2400684. Date of Electronic Publication: 2024 Nov 16.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sumac liposomes/mesenchymal stem cells fight methotrexate-induced nephrotoxicity in rats via regulating Nrf-2/Keap-1/HO-1 and apoptotic signaling pathways.
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  Data: <searchLink fieldCode="AU" term="%22Zahran+EM%22">Zahran EM</searchLink>; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Mohyeldin+RH%22">Mohyeldin RH</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Deraya University, New Minia, Egypt.; Deraya Center for Scientific Research, Deraya University, New Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Refaat+H%22">Refaat H</searchLink>; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Abou-Zied+HA%22">Abou-Zied HA</searchLink>; Department of Medicinal Chemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22ElNaggar+MH%22">ElNaggar MH</searchLink>; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.<br /><searchLink fieldCode="AU" term="%22Abbas+GM%22">Abbas GM</searchLink>; Department of Pharmacognosy, Faculty of Pharmacy, Horus University- Egypt (HUE), New Damietta, Egypt.<br /><searchLink fieldCode="AU" term="%22Maher+SA%22">Maher SA</searchLink>; Department of Biochemistry, Faculty of Pharmacy, New Valley University, El-kharga City, Egypt.<br /><searchLink fieldCode="AU" term="%22Saber+EA%22">Saber EA</searchLink>; Department of Medical Science (Histology and Cell Biology), Faculty of Pharmacy, Deraya University, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Zarka+MA%22">Zarka MA</searchLink>; Department of College of Pharmacy, The Islamic University, Najaf, Iraq.<br /><searchLink fieldCode="AU" term="%22Elrehany+MA%22">Elrehany MA</searchLink>; Department of Biochemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdelmohsen+UR%22">Abdelmohsen UR</searchLink>; Deraya Center for Scientific Research, Deraya University, New Minia, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
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  Data: <searchLink fieldCode="JN" term="%220330167%22">Archiv der Pharmazie</searchLink> [Arch Pharm (Weinheim)] 2025 Jan; Vol. 358 (1), pp. e2400684. <i>Date of Electronic Publication: </i>2024 Nov 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-VCH+Verlag+GmbH+%26+Co%2E+KGaA%22">Wiley-VCH Verlag GmbH & Co. KGaA </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0330167 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-4184 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203656233%22">03656233 </searchLink><i>NLM ISO Abbreviation: </i>Arch Pharm (Weinheim) <i>Subsets: </i>MEDLINE
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