View in EDS HTML Full Text PDF Full Text

An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.

Saved in:
Bibliographic Details
Title: An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.
Authors: Kyriazi D; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Voth L; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Bader A; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Ewert W; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.; Institute for Functional Gene Analytics (IFGA), Bonn-Rhein-Sieg University of Applied Sciences, Rheinbach, Germany., Gerlach J; Faculty of Chemistry, TU Dresden, Dresden, Germany., Elfrink K; Institute of Integrative Cell Biology and Physiology, University of Münster, Münster, Germany., Franz P; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Tsap MI; Institute of Cell Biochemistry, Hannover Medical School, Hannover, Germany., Schirmer B; Institute of Pharmacology, Hannover Medical School, Hannover, Germany., Damiano-Guercio J; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Hartmann FK; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Plenge M; Department of Cell Physiology and Biophysics, Institute of Cell Biology and Biophysics, Leibniz Universität Hannover, Hannover, Germany., Salari A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Schöttelndreier D; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Strienke K; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Bresch N; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Salinas C; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Gutzeit HO; Department of Biology, TU Dresden, Dresden, Germany., Schaumann N; Institute for Pathology, Hannover Medical School, Hannover, Germany., Hussein K; Institute of Pathology, KRH Klinikum Nordstadt, Hannover, Germany., Bähre H; Research Core Unit Mass Spectrometry-Metabolomics, Hannover Medical School, Hanover, Germany., Brüsch I; Institute for Laboratory Animal Science, Hannover Medical School, Hannover, Germany., Claus P; SMATHERIA gGmbH-Non-Profit Biomedical Research Institute, Hannover, Germany., Neumann D; Institute of Pharmacology, Hannover Medical School, Hannover, Germany., Taft MH; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany., Shcherbata HR; Institute of Cell Biochemistry, Hannover Medical School, Hannover, Germany., Ngezahayo A; Department of Cell Physiology and Biophysics, Institute of Cell Biology and Biophysics, Leibniz Universität Hannover, Hannover, Germany., Bähler M; Institute of Integrative Cell Biology and Physiology, University of Münster, Münster, Germany., Amiri M; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Knölker HJ; Faculty of Chemistry, TU Dresden, Dresden, Germany., Preller M; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.; Institute for Functional Gene Analytics (IFGA), Bonn-Rhein-Sieg University of Applied Sciences, Rheinbach, Germany., Tsiavaliaris G; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany. Tsiavaliaris.Georgios@mh-hannover.de.
Source: Nature communications [Nat Commun] 2024 Nov 16; Vol. 15 (1), pp. 9947. Date of Electronic Publication: 2024 Nov 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 39550360
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Kyriazi+D%22">Kyriazi D</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Voth+L%22">Voth L</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Bader+A%22">Bader A</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Ewert+W%22">Ewert W</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.; Institute for Functional Gene Analytics (IFGA), Bonn-Rhein-Sieg University of Applied Sciences, Rheinbach, Germany.<br /><searchLink fieldCode="AU" term="%22Gerlach+J%22">Gerlach J</searchLink>; Faculty of Chemistry, TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Elfrink+K%22">Elfrink K</searchLink>; Institute of Integrative Cell Biology and Physiology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Franz+P%22">Franz P</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Tsap+MI%22">Tsap MI</searchLink>; Institute of Cell Biochemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schirmer+B%22">Schirmer B</searchLink>; Institute of Pharmacology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Damiano-Guercio+J%22">Damiano-Guercio J</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Hartmann+FK%22">Hartmann FK</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Plenge+M%22">Plenge M</searchLink>; Department of Cell Physiology and Biophysics, Institute of Cell Biology and Biophysics, Leibniz Universität Hannover, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Salari+A%22">Salari A</searchLink>; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Schöttelndreier+D%22">Schöttelndreier D</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Strienke+K%22">Strienke K</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Bresch+N%22">Bresch N</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Salinas+C%22">Salinas C</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Gutzeit+HO%22">Gutzeit HO</searchLink>; Department of Biology, TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Schaumann+N%22">Schaumann N</searchLink>; Institute for Pathology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Hussein+K%22">Hussein K</searchLink>; Institute of Pathology, KRH Klinikum Nordstadt, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Bähre+H%22">Bähre H</searchLink>; Research Core Unit Mass Spectrometry-Metabolomics, Hannover Medical School, Hanover, Germany.<br /><searchLink fieldCode="AU" term="%22Brüsch+I%22">Brüsch I</searchLink>; Institute for Laboratory Animal Science, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Claus+P%22">Claus P</searchLink>; SMATHERIA gGmbH-Non-Profit Biomedical Research Institute, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Neumann+D%22">Neumann D</searchLink>; Institute of Pharmacology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Taft+MH%22">Taft MH</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Shcherbata+HR%22">Shcherbata HR</searchLink>; Institute of Cell Biochemistry, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Ngezahayo+A%22">Ngezahayo A</searchLink>; Department of Cell Physiology and Biophysics, Institute of Cell Biology and Biophysics, Leibniz Universität Hannover, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Bähler+M%22">Bähler M</searchLink>; Institute of Integrative Cell Biology and Physiology, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Amiri+M%22">Amiri M</searchLink>; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Knölker+HJ%22">Knölker HJ</searchLink>; Faculty of Chemistry, TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Preller+M%22">Preller M</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany.; Institute for Functional Gene Analytics (IFGA), Bonn-Rhein-Sieg University of Applied Sciences, Rheinbach, Germany.<br /><searchLink fieldCode="AU" term="%22Tsiavaliaris+G%22">Tsiavaliaris G</searchLink>; Institute for Biophysical Chemistry, Hannover Medical School, Hannover, Germany. Tsiavaliaris.Georgios@mh-hannover.de.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Nov 16; Vol. 15 (1), pp. 9947. <i>Date of Electronic Publication: </i>2024 Nov 16.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39550360
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-024-54181-6
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 9947
    Titles:
      – TitleFull: An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Kyriazi D
      – PersonEntity:
          Name:
            NameFull: Voth L
      – PersonEntity:
          Name:
            NameFull: Bader A
      – PersonEntity:
          Name:
            NameFull: Ewert W
      – PersonEntity:
          Name:
            NameFull: Gerlach J
      – PersonEntity:
          Name:
            NameFull: Elfrink K
      – PersonEntity:
          Name:
            NameFull: Franz P
      – PersonEntity:
          Name:
            NameFull: Tsap MI
      – PersonEntity:
          Name:
            NameFull: Schirmer B
      – PersonEntity:
          Name:
            NameFull: Damiano-Guercio J
      – PersonEntity:
          Name:
            NameFull: Hartmann FK
      – PersonEntity:
          Name:
            NameFull: Plenge M
      – PersonEntity:
          Name:
            NameFull: Salari A
      – PersonEntity:
          Name:
            NameFull: Schöttelndreier D
      – PersonEntity:
          Name:
            NameFull: Strienke K
      – PersonEntity:
          Name:
            NameFull: Bresch N
      – PersonEntity:
          Name:
            NameFull: Salinas C
      – PersonEntity:
          Name:
            NameFull: Gutzeit HO
      – PersonEntity:
          Name:
            NameFull: Schaumann N
      – PersonEntity:
          Name:
            NameFull: Hussein K
      – PersonEntity:
          Name:
            NameFull: Bähre H
      – PersonEntity:
          Name:
            NameFull: Brüsch I
      – PersonEntity:
          Name:
            NameFull: Claus P
      – PersonEntity:
          Name:
            NameFull: Neumann D
      – PersonEntity:
          Name:
            NameFull: Taft MH
      – PersonEntity:
          Name:
            NameFull: Shcherbata HR
      – PersonEntity:
          Name:
            NameFull: Ngezahayo A
      – PersonEntity:
          Name:
            NameFull: Bähler M
      – PersonEntity:
          Name:
            NameFull: Amiri M
      – PersonEntity:
          Name:
            NameFull: Knölker HJ
      – PersonEntity:
          Name:
            NameFull: Preller M
      – PersonEntity:
          Name:
            NameFull: Tsiavaliaris G
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 11
              Text: 2024 Nov 16
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 15
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1