Molecular mechanisms restoring olaparib efficacy through ATR/CHK1 pathway inhibition in olaparib-resistant BRCA1/2MUT ovarian cancer models.
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| Title: | Molecular mechanisms restoring olaparib efficacy through ATR/CHK1 pathway inhibition in olaparib-resistant BRCA1/2MUT ovarian cancer models. |
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| Authors: | Biegała Ł; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: lukasz.biegala@edu.uni.lodz.pl., Statkiewicz M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 5 Roentgena Street, 02-781 Warsaw, Poland. Electronic address: malgorzata.statkiewicz@nio.gov.pl., Gajek A; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: arkadiusz.gajek@biol.uni.lodz.pl., Szymczak-Pajor I; Department of Nucleic Acid Biochemistry, Medical University of Lodz, 251 Pomorska Street, 92-213 Lodz, Poland. Electronic address: izabela.szymczak@umed.lodz.pl., Rusetska N; Department of Experimental Immunology, Maria Sklodowska-Curie National Research Institute of Oncology, 5 Roentgena Street, 02-781 Warsaw, Poland. Electronic address: natalia.rusetska@nio.gov.pl., Śliwińska A; Department of Nucleic Acid Biochemistry, Medical University of Lodz, 251 Pomorska Street, 92-213 Lodz, Poland. Electronic address: agnieszka.sliwinska@umed.lodz.pl., Marczak A; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: agnieszka.marczak@biol.uni.lodz.pl., Mikula M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 5 Roentgena Street, 02-781 Warsaw, Poland. Electronic address: michal.mikula@nio.gov.pl., Rogalska A; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: aneta.rogalska@biol.uni.lodz.pl. |
| Source: | Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2025 Feb; Vol. 1871 (2), pp. 167574. Date of Electronic Publication: 2024 Nov 16. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39557132 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Molecular mechanisms restoring olaparib efficacy through ATR/CHK1 pathway inhibition in olaparib-resistant BRCA1/2<superscript>MUT</superscript> ovarian cancer models. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Biegała+Ł%22">Biegała Ł</searchLink>; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: lukasz.biegala@edu.uni.lodz.pl.<br /><searchLink fieldCode="AU" term="%22Statkiewicz+M%22">Statkiewicz M</searchLink>; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 5 Roentgena Street, 02-781 Warsaw, Poland. Electronic address: malgorzata.statkiewicz@nio.gov.pl.<br /><searchLink fieldCode="AU" term="%22Gajek+A%22">Gajek A</searchLink>; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: arkadiusz.gajek@biol.uni.lodz.pl.<br /><searchLink fieldCode="AU" term="%22Szymczak-Pajor+I%22">Szymczak-Pajor I</searchLink>; Department of Nucleic Acid Biochemistry, Medical University of Lodz, 251 Pomorska Street, 92-213 Lodz, Poland. Electronic address: izabela.szymczak@umed.lodz.pl.<br /><searchLink fieldCode="AU" term="%22Rusetska+N%22">Rusetska N</searchLink>; Department of Experimental Immunology, Maria Sklodowska-Curie National Research Institute of Oncology, 5 Roentgena Street, 02-781 Warsaw, Poland. Electronic address: natalia.rusetska@nio.gov.pl.<br /><searchLink fieldCode="AU" term="%22Śliwińska+A%22">Śliwińska A</searchLink>; Department of Nucleic Acid Biochemistry, Medical University of Lodz, 251 Pomorska Street, 92-213 Lodz, Poland. Electronic address: agnieszka.sliwinska@umed.lodz.pl.<br /><searchLink fieldCode="AU" term="%22Marczak+A%22">Marczak A</searchLink>; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: agnieszka.marczak@biol.uni.lodz.pl.<br /><searchLink fieldCode="AU" term="%22Mikula+M%22">Mikula M</searchLink>; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 5 Roentgena Street, 02-781 Warsaw, Poland. Electronic address: michal.mikula@nio.gov.pl.<br /><searchLink fieldCode="AU" term="%22Rogalska+A%22">Rogalska A</searchLink>; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, 141/143 Pomorska Street, 90-236 Lodz, Poland. Electronic address: aneta.rogalska@biol.uni.lodz.pl. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101731730%22">Biochimica et biophysica acta. Molecular basis of disease</searchLink> [Biochim Biophys Acta Mol Basis Dis] 2025 Feb; Vol. 1871 (2), pp. 167574. <i>Date of Electronic Publication: </i>2024 Nov 16. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101731730 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-260X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209254439%22">09254439 </searchLink><i>NLM ISO Abbreviation: </i>Biochim Biophys Acta Mol Basis Dis <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bbadis.2024.167574 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 167574 Titles: – TitleFull: Molecular mechanisms restoring olaparib efficacy through ATR/CHK1 pathway inhibition in olaparib-resistant BRCA1/2MUT ovarian cancer models. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Biegała Ł – PersonEntity: Name: NameFull: Statkiewicz M – PersonEntity: Name: NameFull: Gajek A – PersonEntity: Name: NameFull: Szymczak-Pajor I – PersonEntity: Name: NameFull: Rusetska N – PersonEntity: Name: NameFull: Śliwińska A – PersonEntity: Name: NameFull: Marczak A – PersonEntity: Name: NameFull: Mikula M – PersonEntity: Name: NameFull: Rogalska A IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2025 Feb Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1879-260X Numbering: – Type: volume Value: 1871 – Type: issue Value: 2 Titles: – TitleFull: Biochimica et biophysica acta. Molecular basis of disease Type: main |
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