Methylation cytometric pretreatment blood immune profiles with tumor mutation burden as prognostic indicators for survival outcomes in head and neck cancer patients on anti-PD-1 therapy.

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Title: Methylation cytometric pretreatment blood immune profiles with tumor mutation burden as prognostic indicators for survival outcomes in head and neck cancer patients on anti-PD-1 therapy.
Authors: Zhang Z; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA. ze.zhang.gr@dartmouth.edu.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA. ze.zhang.gr@dartmouth.edu., Sehgal K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Shirai K; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA., Butler RA; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Wiencke JK; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA., Koestler DC; Department of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA., Ramush G; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Lee MK; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA., Molinaro AM; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA., Stolrow HG; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA., Birnbaum A; Department of Medicine, Rhode Island Hospital, Providence, RI, USA., Salas LA; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA., Haddad RI; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kelsey KT; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA., Christensen BC; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.
Source: NPJ precision oncology [NPJ Precis Oncol] 2024 Nov 18; Vol. 8 (1), pp. 267. Date of Electronic Publication: 2024 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE
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  Data: Methylation cytometric pretreatment blood immune profiles with tumor mutation burden as prognostic indicators for survival outcomes in head and neck cancer patients on anti-PD-1 therapy.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA. ze.zhang.gr@dartmouth.edu.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA. ze.zhang.gr@dartmouth.edu.<br /><searchLink fieldCode="AU" term="%22Sehgal+K%22">Sehgal K</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shirai+K%22">Shirai K</searchLink>; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.<br /><searchLink fieldCode="AU" term="%22Butler+RA%22">Butler RA</searchLink>; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Wiencke+JK%22">Wiencke JK</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Koestler+DC%22">Koestler DC</searchLink>; Department of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS, USA.<br /><searchLink fieldCode="AU" term="%22Ramush+G%22">Ramush G</searchLink>; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Lee+MK%22">Lee MK</searchLink>; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.<br /><searchLink fieldCode="AU" term="%22Molinaro+AM%22">Molinaro AM</searchLink>; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stolrow+HG%22">Stolrow HG</searchLink>; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.<br /><searchLink fieldCode="AU" term="%22Birnbaum+A%22">Birnbaum A</searchLink>; Department of Medicine, Rhode Island Hospital, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Salas+LA%22">Salas LA</searchLink>; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.<br /><searchLink fieldCode="AU" term="%22Haddad+RI%22">Haddad RI</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kelsey+KT%22">Kelsey KT</searchLink>; Department of Epidemiology, School of Public Health, Brown University, Providence, RI, USA.; Department of Pathology and Laboratory Medicine, Brown University, Providence, RI, USA.<br /><searchLink fieldCode="AU" term="%22Christensen+BC%22">Christensen BC</searchLink>; Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.; Dartmouth Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101708166 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2397-768X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222397768X%22">2397768X </searchLink><i>NLM ISO Abbreviation: </i>NPJ Precis Oncol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41698-024-00759-8
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