Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape.

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Title: Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape.
Authors: Chabot BJ; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA., Sun R; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA., Amjad A; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA., Hoyt SJ; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA., Ouyang L; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA., Courret C; Department of Biology, University of Rochester, Rochester, NY, USA., Drennan R; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA., Leo L; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.; Department of Biology and Biotechnology, Sapienza University of Rome, 00185, Rome, Italy.; Present Address: RNA Editing Lab, Onco-Haematology Department, Genetics and Epigenetics of Pediatric Cancers, Bambino Gesù Children Hospital, IRCCS, 00146, Rome, Italy., Larracuente AM; Department of Biology, University of Rochester, Rochester, NY, USA., Core LJ; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA., O'Neill RJ; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA.; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA., Mellone BG; Department of Molecular and Cell Biology, University of Connecticut, Storrs, CT, USA. Barbara.Mellone@uconn.edu.; Institute for Systems Genomics, University of Connecticut, Storrs, CT, USA. Barbara.Mellone@uconn.edu.
Source: Genome biology [Genome Biol] 2024 Nov 18; Vol. 25 (1), pp. 295. Date of Electronic Publication: 2024 Nov 18.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1474-760X
DOI:10.1186/s13059-024-03433-1