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The SGLT2 inhibitor empagliflozin exerts neuroprotective effect against hydrogen peroxide-induced toxicity on primary neurons.

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Title: The SGLT2 inhibitor empagliflozin exerts neuroprotective effect against hydrogen peroxide-induced toxicity on primary neurons.
Authors: Davri AS; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Department of Pathology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece., Katsenos AP; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece., Tulyaganova GK; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece., Tzavellas NP; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece., Simos YV; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece., Kanellos FS; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece., Konitsiotis S; Department of Neurology, Faculty of Medicine, School of Health Sciences, University Hospital of Ioannina, Ioannina, 45110, Greece., Dounousi E; Department of Nephrology, Faculty of Medicine, School of Health Sciences, Dialysis Center, University of Ιoannina, Nephroxenia Ioannina, Ioannina, 45110, Greece., Niaka K; Department of Biological Applications and Technology, School of Health Sciences, Institute of Biosciences, University Research Centre, University of Ioannina, Ioannina, 45110, Greece., Bellou S; Biomedical Research Institute, University of Ioannina Network of Research Supporting Laboratories (NRSL) Confocal Laser Scanning Microscopy Unit and Foundation for Research & Technology-Hellas, University Campus, Ioannina, 45110, Greece., Lekkas P; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece., Bekiari C; Laboratory of Anatomy, Histology & Embryology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece., Batistatou A; Department of Pathology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece., Peschos D; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece., Tsamis KI; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece. ktsamis@uoi.gr.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece. ktsamis@uoi.gr.; Department of Neurology, Faculty of Medicine, School of Health Sciences, University Hospital of Ioannina, Ioannina, 45110, Greece. ktsamis@uoi.gr.
Source: Metabolic brain disease [Metab Brain Dis] 2024 Nov 19; Vol. 40 (1), pp. 15. Date of Electronic Publication: 2024 Nov 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8610370 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7365 (Electronic) Linking ISSN: 08857490 NLM ISO Abbreviation: Metab Brain Dis Subsets: MEDLINE
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  Data: The SGLT2 inhibitor empagliflozin exerts neuroprotective effect against hydrogen peroxide-induced toxicity on primary neurons.
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  Data: <searchLink fieldCode="AU" term="%22Davri+AS%22">Davri AS</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Department of Pathology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Katsenos+AP%22">Katsenos AP</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Tulyaganova+GK%22">Tulyaganova GK</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Tzavellas+NP%22">Tzavellas NP</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Simos+YV%22">Simos YV</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Kanellos+FS%22">Kanellos FS</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Konitsiotis+S%22">Konitsiotis S</searchLink>; Department of Neurology, Faculty of Medicine, School of Health Sciences, University Hospital of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Dounousi+E%22">Dounousi E</searchLink>; Department of Nephrology, Faculty of Medicine, School of Health Sciences, Dialysis Center, University of Ιoannina, Nephroxenia Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Niaka+K%22">Niaka K</searchLink>; Department of Biological Applications and Technology, School of Health Sciences, Institute of Biosciences, University Research Centre, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Bellou+S%22">Bellou S</searchLink>; Biomedical Research Institute, University of Ioannina Network of Research Supporting Laboratories (NRSL) Confocal Laser Scanning Microscopy Unit and Foundation for Research & Technology-Hellas, University Campus, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Lekkas+P%22">Lekkas P</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Bekiari+C%22">Bekiari C</searchLink>; Laboratory of Anatomy, Histology & Embryology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Batistatou+A%22">Batistatou A</searchLink>; Department of Pathology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Peschos+D%22">Peschos D</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece.<br /><searchLink fieldCode="AU" term="%22Tsamis+KI%22">Tsamis KI</searchLink>; Laboratory of Physiology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, 45110, Greece. ktsamis@uoi.gr.; Nanomedicine and Nanobiotechnology Research Group, University of Ioannina, Ioannina, 45110, Greece. ktsamis@uoi.gr.; Department of Neurology, Faculty of Medicine, School of Health Sciences, University Hospital of Ioannina, Ioannina, 45110, Greece. ktsamis@uoi.gr.
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